YRC Public Data Repository - Protein Structure Prediction

Protein:	AGAR_ECOLI
Organism:	Escherichia coli
Length:	269 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AGAR_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|115514811, gi... - gi\|117625687\|ref\|YP_859010.1\| DNA-binding transcriptional repressor GlpR [Escherichia coli APEC O1],...	240.0	[0..1]	[267..1]
gi\|83571653 - gi\|83571653\|ref\|ZP_00923093.1\| COG1349: Transcriptional regulators of sugar metabolism [Shigella dys...	240.0	[0..1]	[267..1]
gi\|75241487 - gi\|75241487\|ref\|ZP_00725332.1\| COG1349: Transcriptional regulators of sugar metabolism [Escherichia ...	239.0	[0..1]	[267..1]
gi\|91074471, gi\|... - gi\|91212897\|ref\|YP_542883.1\| DNA-binding transcriptional repressor GlpR [Escherichia coli UTI89], gi... gi\|237703154, gi... - gi\|237703154\|ref\|ZP_04533635.1\| glycerol-3-phosphate regulon repressor [Escherichia sp. 3_2_53FAA], ... gi\|26110453, gi\|... - gi\|26250024\|ref\|NP_756064.1\| DNA-binding transcriptional repressor GlpR [Escherichia coli CFT073], g...	239.0	[0..1]	[267..6]
gi\|83588713 - gi\|83588713\|ref\|ZP_00927337.1\| COG1349: Transcriptional regulators of sugar metabolism [Escherichia ...	237.0	[0..1]	[267..1]
gi\|83653168, gi\|... - gi\|83719343\|ref\|YP_441160.1\| glycerol-3-phosphate regulon repressor [Burkholderia thailandensis E264...	236.0	[0..6]	[268..19]
gi\|74014263, gi\|... - gi\|74014263\|ref\|ZP_00684892.1\| regulatory protein, DeoR [Burkholderia ambifaria AMMD], gi\|72612865\|g...	236.0	[0..2]	[268..27]
gi\|157080898, gi... - gi\|75187937\|ref\|ZP_00701204.1\| COG1349: Transcriptional regulators of sugar metabolism [Escherichia ...	236.0	[0..1]	[269..1]
gi\|77960956, gi\|... - gi\|77960956\|ref\|ZP_00824807.1\| COG1349: Transcriptional regulators of sugar metabolism [Yersinia mol...	236.0	[0..13]	[269..1]
gi\|238783818, gi... - gi\|77958943\|ref\|ZP_00822968.1\| COG1349: Transcriptional regulators of sugar metabolism [Yersinia ber...	236.0	[0..13]	[269..1]

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Predicted Domain #1

Region A:
Residues: [1-88]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNTDASGEK RVTGTSERRE QIIQRLRQQG SVQVNDLSAL YGVSTVTIRN DLAFLEKQGI  60
   61 AVRAYGGALI CDSTTPSVEP SVEDKSAL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.69897
Match:	2p5vA
Description:	No description for 2p5vA was found.

Predicted Domain #2

Region A:
Residues: [89-269]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTAMKRSVAK AAVELIQPGH RVILDSGTTT FEIARLMRKH TDVIAMTNGM NVANALLEAE  60
   61 GVELLMTGGH LRRQSQSFYG DQAEQSLQNY HFDMLFLGVD AIDLERGVST HNEDEARLNR 120
  121 RMCEVAERII VVTDSSKFNR SSLHKIIDTQ RIDMIIVDEG IPADSLEGLR KAGVEVILVG 180
  181 E

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	11.30103
Match:	1oozA
Description:	Deletion mutant of SUCCINYL-COA:3-KETOACID COA TRANSFERASE FROM PIG HEART
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.68776709414398	bayes_pls_golite062009
nucleic acid binding	0.965520574888216	bayes_pls_golite062009
transcription regulator activity	0.769423781192988	bayes_pls_golite062009
DNA binding	0.223734115868557	bayes_pls_golite062009
binding	0.199466104892993	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: