YRC Public Data Repository - Protein Structure Prediction

Protein:	ADPP_ECOLI
Organism:	Escherichia coli
Length:	209 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ADPP_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|14627087 - gi\|14627087\|emb\|CAC44036.1\| adenosine diphosphate sugar pyrophosphatase [Escherichia coli] gi\|14627087\|emb\|... - adenosine diphosphate sugar pyrophosphatase [Escherichia coli]	205.0	[0..1]	[209..1]
gi\|66043814, gi\|... - gi\|66043814\|ref\|YP_233655.1\| hypothetical protein Psyr_0547 [Pseudomonas syringae pv. syringae B728a...	204.0	[0..3]	[209..9]
gi\|110344872, gi... - gi\|110643280\|ref\|YP_671010.1\| ADP-ribose pyrophosphatase NudF [Escherichia coli 536], gi\|110344872\|g...	204.0	[0..1]	[209..1]
gi\|82545291, gi\|... - gi\|82545291\|ref\|YP_409238.1\| ADP-ribose pyrophosphatase NudF [Shigella boydii Sb227], gi\|81246702\|gb...	203.0	[0..1]	[209..1]
gi\|195633661, gi... - gi\|195633661\|gb\|EDX52075.1\| hydrolase, NUDIX family [Salmonella enterica subsp. enterica serovar New... gi\|168262857, gi... - gi\|205348594\|gb\|EDZ35225.1\| hydrolase, NUDIX family [Salmonella enterica subsp. enterica serovar Had... gi\|205337887, gi... - gi\|205337887\|gb\|EDZ24651.1\| hydrolase, NUDIX family [Salmonella enterica subsp. enterica serovar Hei... gi\|197288969, gi... - gi\|197288969\|gb\|EDY28340.1\| hydrolase, NUDIX family protein [Salmonella enterica subsp. enterica ser... gi\|62129332, gi\|... - gi\|62181699\|ref\|YP_218116.1\| ADP-ribose pyrophosphatase NudF [Salmonella enterica subsp. enterica se... gi\|205333872, gi... - gi\|205333872\|gb\|EDZ20636.1\| hydrolase, NUDIX family [Salmonella enterica subsp. enterica serovar Ken... gi\|205323325, gi... - gi\|205323325\|gb\|EDZ11164.1\| hydrolase, NUDIX family [Salmonella enterica subsp. enterica serovar Sai... gi\|238909986 - gi\|238909986\|ref\|ZP_04653823.1\| ADP-ribose pyrophosphatase NudF [Salmonella enterica subsp. enterica... gi\|224584986, gi... - gi\|224584986\|ref\|YP_002638785.1\| hypothetical protein SPC_3259 [Salmonella enterica subsp. enterica ... gi\|204928165, gi... - gi\|204928165\|ref\|ZP_03219365.1\| hydrolase, NUDIX family [Salmonella enterica subsp. enterica serovar... gi\|199605157, gi... - gi\|200388059\|ref\|ZP_03214671.1\| hydrolase, NUDIX family [Salmonella enterica subsp. enterica serovar... gi\|197249833, gi... - gi\|197249833\|ref\|YP_002148112.1\| hydrolase, NUDIX family [Salmonella enterica subsp. enterica serova... gi\|194710227, gi... - gi\|194734725\|ref\|YP_002116140.1\| hydrolase, NUDIX family [Salmonella enterica subsp. enterica serova... gi\|194469990, gi... - gi\|194469990\|ref\|ZP_03075974.1\| hydrolase, NUDIX family [Salmonella enterica subsp. enterica serovar... gi\|194450031, gi... - gi\|194450031\|ref\|YP_002047182.1\| ADP-ribose pyrophosphatase NudF [Salmonella enterica subsp. enteric... gi\|194442306, gi... - gi\|194442306\|ref\|YP_002042452.1\| hydrolase, NUDIX family [Salmonella enterica subsp. enterica serova... gi\|168819752, gi... - gi\|205343414\|gb\|EDZ30178.1\| hydrolase, NUDIX family [Salmonella enterica subsp. enterica serovar Wel...	202.0	[0..1]	[208..1]
gi\|205354101, gi... - gi\|205354101\|ref\|YP_002227902.1\| ADP-ribose pyrophosphatase NudF [Salmonella enterica subsp. enteric... gi\|198243748, gi... - gi\|198243748\|ref\|YP_002217165.1\| hydrolase, NUDIX family [Salmonella enterica subsp. enterica serova... gi\|197364055, gi... - gi\|197364055\|ref\|YP_002143692.1\| ADP-ribose pyrophosphatase NudF [Salmonella enterica subsp. enteric... gi\|197240165, gi... - gi\|197261910\|ref\|ZP_03161984.1\| hydrolase, NUDIX family [Salmonella enterica subsp. enterica serovar... gi\|213424341 - gi\|213424341\|ref\|ZP_03357165.1\| ADP-ribose pyrophosphatase NudF [Salmonella enterica subsp. enterica... gi\|213419639 - gi\|213419639\|ref\|ZP_03352705.1\| ADP-ribose pyrophosphatase NudF [Salmonella enterica subsp. enterica... gi\|213052522 - gi\|213052522\|ref\|ZP_03345400.1\| ADP-ribose pyrophosphatase NudF [Salmonella enterica subsp. enterica... gi\|207858444, gi... - gi\|207858444\|ref\|YP_002245095.1\| ADP-ribose pyrophosphatase NudF [Salmonella enterica subsp. enteric... gi\|205331205, gi... - gi\|205331205\|gb\|EDZ17969.1\| hydrolase, NUDIX family [Salmonella enterica subsp. enterica serovar 4,[... gi\|25303394, gi\|... - gi\|25303394\|pir\|\|AI0889 conserved hypothetical protein STY3363 [imported] - Salmonella enterica subs... gi\|56129383, gi\|... - gi\|56415126\|ref\|YP_152201.1\| ADP-ribose pyrophosphatase NudF [Salmonella enterica subsp. enterica se... gi\|16421741, gi\|... - gi\|16766485\|ref\|NP_462100.1\| ADP-ribose pyrophosphatase NudF [Salmonella typhimurium LT2], gi\|164217... gi\|29143447, gi\|... - gi\|29143447\|ref\|NP_806789.1\| ADP-ribose pyrophosphatase NudF [Salmonella enterica subsp. enterica se... gi\|16761960 - gi\|16761960\|ref\|NP_457577.1\| ADP-ribose pyrophosphatase NudF [Salmonella enterica subsp. enterica se... gi\|213855668 - gi\|213855668\|ref\|ZP_03383908.1\| ADP-ribose pyrophosphatase NudF [Salmonella enterica subsp. enterica... lcl\|NC_016856.1_... - [gene=nudF] [protein=ADP-ribose pyrophosphatase NudF] [protein_id=YP_005239357.1] [location=compleme... gi\|213645893 - gi\|213645893\|ref\|ZP_03375946.1\| ADP-ribose pyrophosphatase NudF [Salmonella enterica subsp. enterica... gi\|213622048 - gi\|213622048\|ref\|ZP_03374831.1\| ADP-ribose pyrophosphatase NudF [Salmonella enterica subsp. enterica... gi\|213583542 - gi\|213583542\|ref\|ZP_03365368.1\| ADP-ribose pyrophosphatase NudF [Salmonella enterica subsp. enterica... gi\|214001840 - gi\|214001840\|ref\|ZP_03412575.1\| ADP-ribose pyrophosphatase NudF [Salmonella enterica subsp. enterica...	202.0	[0..1]	[208..1]
gi\|238793659, gi... - gi\|77978331\|ref\|ZP_00833762.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ...	202.0	[0..1]	[208..1]
gi\|110806927, gi... - gi\|110806927\|ref\|YP_690447.1\| ADP-ribose pyrophosphatase NudF [Shigella flexneri 5 str. 8401], gi\|11...	202.0	[0..1]	[209..1]
gi\|86148727, gi\|... - gi\|86148727\|ref\|ZP_01067002.1\| MutT/nudix family protein [Vibrio sp. MED222], gi\|85833476\|gb\|EAQ5165...	201.0	[0..1]	[208..1]
tr\|Q87VG4\|Q87VG4... - MutT/nudix family protein OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=PSPTO_4973 PE=3 SV=1 gi\|28872087, gi\|... - gi\|28872087\|ref\|NP_794706.1\| mutT/nudix family protein [Pseudomonas syringae pv. tomato str. DC3000]... gi\|213967896, gi... - gi\|213967896\|ref\|ZP_03396042.1\| mutT/nudix family protein [Pseudomonas syringae pv. tomato T1], gi\|2...	201.0	[0..5]	[209..1]

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Predicted Domain #1

Region A:
Residues: [1-209]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKPDNLPVT FGKNDVEIIA RETLYRGFFS LDLYRFRHRL FNGQMSHEVR REIFERGHAA  60
   61 VLLPFDPVRD EVVLIEQIRI AAYDTSETPW LLEMVAGMIE EGESVEDVAR REAIEEAGLI 120
  121 VKRTKPVLSF LASPGGTSER SSIMVGEVDA TTASGIHGLA DENEDIRVHV VSREQAYQWV 180
  181 EEGKIDNAAS VIALQWLQLH HQALKNEWA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.0
Match:	1g0sA
Description:	ADP-ribose pyrophosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.49075808737475	bayes_pls_golite062009
hydrolase activity	1.0879699007552	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.859040726089354	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.859001295204634	bayes_pls_golite062009
pyrophosphatase activity	0.231401568856773	bayes_pls_golite062009
binding	0.165092558977235	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: