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View Structure Prediction Details

Protein: zyg-12
Organism: Caenorhabditis elegans
Length: 761 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for zyg-12.

Description E-value Query
Range
Subject
Range
gi|68388302 - gi|68388302|ref|XP_696268.1| PREDICTED: similar to slow myosin heavy chain 1 [Danio rerio]
237.0 [0..10] [685..2251]

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Predicted Domain #1
Region A:
Residues: [1-188]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDLTNKESE SSDNGNSKYE DSIDGREVGT SKPFKEERSL EDLQADLADM AVWMEGLDAT  60
   61 KLPLNDPQLL CNGRAFSEVL HNVDKNFFTD GWLETMPENR TTNIMVFRSC TRKLWRKMFD 120
  121 YVNHINRTVV SSRWTDIHER IDGIYESDLP AMVNLGMAVV TLAHIGKNAK RFVDYSKALT 180
  181 STHKSMMS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.0
Match: 1wixA
Description: The solution structure of RSGI RUH-026, conserved domain of HOOK1 protein from mouse
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.77302826695282 bayes_pls_golite062009
protein binding 1.34258839710246 bayes_pls_golite062009
microtubule binding 0.26034159312323 bayes_pls_golite062009
tubulin binding 0.11464228697646 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [189-277]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVAKMVTTVI DEMPENPCFH EISELHGSQS ELNSLSESSG KLNGNGSSER RSNADQILVD  60
   61 AELEIERLRT ETENQRKEIE RLTKSFETA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.30103
Match: 2fxmA
Description: No description for 2fxmA was found.

Predicted Domain #3
Region A:
Residues: [278-417]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QHDMSSNSES GDISILEKQN EELRQKRREL EEKNLELDAA VDQFKGIVFE LTNENDVLRR  60
   61 SDKERQRLQT VLDAAQSDLD EWKTVANQYQ KEAELSKQQD KEIKELLSQN KALKSRLDHH 120
  121 VKSATLEDAN KNGIAQLRTQ 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.74
Match: 1jchA
Description: Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [418-761]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGGLTALNTE LKASLDSKKR CVEQLEIQLI QHKEKVKELE DRKDELIEER NRLENQLIFK  60
   61 EAVTPRSLHE SMFEAGNLSF EPFSEKNTLP LEIENKRLTE RIQELESLEP LKGELITLKS 120
  121 KNGVLEEEKL FATKQIEELQ QQIEDLQENL LKNQEHASGD VVGLKIQLEK AEVEAQQMRE 180
  181 AKMRAETNQA QVDEILKKRT AELEVNATAL QKAKAVIDEL EYNSRPVSED SMTSVQAFKE 240
  241 MKEENEKLRQ KVEKLEIELN TVTQGFEQEN RLLTSASHQQ VLNRSIDEVM SMRAHAGSEE 300
  301 PQTLLDTQKM SGALPWSILV LGFLVFIAWM FININSALNA PPNA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.69897
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
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