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View Structure Prediction Details

Protein: tbx-9
Organism: Caenorhabditis elegans
Length: 292 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tbx-9.

Description E-value Query
Range
Subject
Range
gi|73973880 - gi|73973880|ref|XP_539024.2| PREDICTED: similar to T-box transcription factor TBX18 (T-box protein 1...
305.0 [0..7] [284..771]

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Predicted Domain #1
Region A:
Residues: [1-203]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKVKVSIEG SQETLWKIFH AEVNEMIVTK NGRKLFPKLE YIVEGLDENK LYAIMLQLQP  60
   61 VGESRFKFSG GKWQETGKAE KQVDAKKMWH ADGVRKGSDW MWSSICFDRV KISNYSESNN 120
  121 ASMIYLNSMH KYIPVLTIYE SPSESPFCVP QSSNQIVATA KFPHTEFIAV TAYQNQKITD 180
  181 LKIKHNSFAK GFRDGNLSRK RRS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 75.154902
Match: 1h6fA
Description: T-box protein 3, tbx3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.42929256050781 bayes_pls_golite062009
DNA binding 5.31133900263778 bayes_pls_golite062009
nucleic acid binding 5.16722510757739 bayes_pls_golite062009
transcription factor activity 4.50526425463039 bayes_pls_golite062009
binding 3.82913410895101 bayes_pls_golite062009
sequence-specific DNA binding 2.81812565096059 bayes_pls_golite062009
protein binding 2.61625563263605 bayes_pls_golite062009
transcription activator activity 2.56828839945617 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.23604897773023 bayes_pls_golite062009
DNA strand annealing activity 1.36275472058409 bayes_pls_golite062009
transcription repressor activity 1.27337392672914 bayes_pls_golite062009
structure-specific DNA binding 0.6498675574078 bayes_pls_golite062009
chromatin binding 0.63177553202971 bayes_pls_golite062009
transcription factor binding 0.628837188707778 bayes_pls_golite062009
double-stranded DNA binding 0.62643527396553 bayes_pls_golite062009
single-stranded DNA binding 0.0996675597396202 bayes_pls_golite062009
protein dimerization activity 0.0889583851427092 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [204-292]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSYSDGSNSQ SPSPKSRSPP EVAPLQSMPP INPFLFYFPH MLSENLPVQF PFAFPFLSPL  60
   61 PSTPSSSSSE LSIVKEEDQE VEEDIDIVG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle