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View Structure Prediction Details

Protein: tag-72
Organism: Caenorhabditis elegans
Length: 380 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tag-72.

Description E-value Query
Range
Subject
Range
MCES_CAEBR - mRNA cap guanine-N7 methyltransferase OS=Caenorhabditis briggsae GN=tag-72 PE=3 SV=1
gi|157746911 - gi|157746911|ref|XP_001668550.1| Hypothetical protein CBG12234 [Caenorhabditis briggsae AF16]
221.0 [0..1] [362..1]

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Predicted Domain #1
Region A:
Residues: [1-380]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSEVASHY NKVLQVGIEG RKESRIFFMR NMNNWVKSQL INDAKQRVND NGVNNPRVLD  60
   61 LACGKGGDLK KWDIAGAKDV VMADVADVSI QQAEERYKQM FGYKKNNIFT VQFIVADCTK 120
  121 ENLEDRIENK DPFDLVSCQF ALHYSFVDEA SARIFLKNAV GMLKPGGVFI GTLPDADRIV 180
  181 WSMRNGENGQ FANEVCKITY ENVEELAEGK VPLFGAKFHF SLDEQVNCPE FLAYFPLVKH 240
  241 LLEELDMELL FVHNFAEAIN KWLEPGRRLL ESMTGLETYP NEKLSGKSDD EYLEAKAKLD 300
  301 AFPEDERIKT MGTLSKSEWE AICMYLVFGF RKKKSEAEKT EEEPATTKPV AESESEQKEV 360
  361 TESEEKEDQE DCEHQEAQTN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.0
Match: 1ri1A
Description: Structure and mechanism of mRNA cap (guanine N-7) methyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
mRNA (guanine-N7-)-methyltransferase activity 4.23788594273427 bayes_pls_golite062009
mRNA methyltransferase activity 4.23788594273427 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 2.50181720310228 bayes_pls_golite062009
methyltransferase activity 2.39031546273566 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 2.30769384783609 bayes_pls_golite062009
N-methyltransferase activity 2.26670816231281 bayes_pls_golite062009
RNA methyltransferase activity 1.86200407013263 bayes_pls_golite062009
rRNA methyltransferase activity 1.3386061065513 bayes_pls_golite062009
catalytic activity 1.25333584501255 bayes_pls_golite062009
RNA binding 1.10729923226801 bayes_pls_golite062009
transferase activity 1.07321114919891 bayes_pls_golite062009
transcription regulator activity 0.914549843668268 bayes_pls_golite062009
tRNA methyltransferase activity 0.868107614027708 bayes_pls_golite062009
DNA binding 0.86027591375666 bayes_pls_golite062009
nucleic acid binding 0.616949327277483 bayes_pls_golite062009
binding 0.383237930789959 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle