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View Structure Prediction Details

Protein: egl-8
Organism: Caenorhabditis elegans
Length: 592 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for egl-8.

Description E-value Query
Range
Subject
Range
gi|73991315 - gi|73991315|ref|XP_859627.1| PREDICTED: similar to 1-phosphatidylinositol-4,5-bisphosphate phosphodi...
555.0 [0..1] [575..1]

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Predicted Domain #1
Region A:
Residues: [1-592]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKEFQFNWK PTIIPELLHG SVFDRYDDES TCLELNAQVR IDENGFFLRW LIEGKDAVVL  60
   61 DMGQIWEART GGLPKDGRIM FELEQRGASE TIAERTIWIT HGQDLVNVQS FFLVAESVEL 120
  121 AKTCRAGIND ILKSSRIRHV CPTTQLMKYH TWLTMNVNER RKIPIKLIIK TFSSGKPEKM 180
  181 VQKCLNDLGL GGDKYTPARV INRSMGKKFR NFYKCSRGRK RKEREELDVD ILTFEKFQRL 240
  241 YNKICPRTEV QELFVKLSGQ KEYLTKERLI NFLNEEQRDP RLNEILFPFF DSQRIVALLK 300
  301 KHENDIKYQE DGKMSGDGFL RFLMSDENPP VFLDRIEMFM DMDQPLCHYY INSSHNTYLT 360
  361 GRQYGGKSSS EIYRQVLLSG CRCIELDCWD GTGENKGEPI ITHGKAMCTD VFFKDVLVQI 420
  421 RDTAFARSDF PVVLSFENHC SKSNQLKMAK YCMDIFGDML LSKPFEDAPL DPGVSLPSPN 480
  481 RLRKKILIKN KRLKTDIERH QLDQFLREGK LDEEDELNET PEVVGEDSVS PREMPAKEND 540
  541 EAHPELKQNF IAKNLKGFGF SKKQETNKIS NFNIVFKGFL FLLILILLSQ IP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 141.0
Match: 2fjuB
Description: No description for 2fjuB was found.

Predicted functions:

Term Confidence Notes
binding 0.597587183571285 bayes_pls_golite062009
protein binding 0.29116370406325 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.05056572092175 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.0304825793447705 bayes_pls_golite062009
phosphoric diester hydrolase activity 0.01534375493934 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle