YRC Public Data Repository - Protein Structure Prediction

Protein:	BET4
Organism:	Saccharomyces cerevisiae
Length:	327 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BET4.

Description	E-value	Query Range	Subject Range
gi\|5052534 - gi\|5052534\|gb\|AAD38597.1\|AF145622_1 BcDNA.GH04245 [Drosophila melanogaster]	6.0E-41	[5..327]	[129..435]
gi\|13775066 - gi\|13775066\|gb\|AAK39123.1\|AF363030_1 UDP-N-acetylglucosaminyltransferase [Mus musculus]	9.0E-40	[5..327]	[100..406]
gi\|31873825 - gi\|31873825\|emb\|CAD97853.1\| hypothetical protein [Homo sapiens]	1.0E-39	[5..327]	[100..406]
OGT1_RAT - UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Rattus norvegicu...	1.0E-39	[5..327]	[90..396]
gi\|187026390, gi... - gi\|39594033\|emb\|CAE70143.1\| Hypothetical protein CBG16605 [Caenorhabditis briggsae], gi\|187026390\|em... gi\|157774869 - gi\|157774869\|ref\|XP_001665500.1\| hypothetical protein CBG16605 [Caenorhabditis briggsae AF16]	5.0E-39	[18..327]	[180..507]

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Predicted Domain #1

Region A:
Residues: [1-242]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHGIKRKQWT KELLRQKRVQ DEKKIYDYRS LTENVLNMRD EKIYSIEALK KTSELLEKNP  60
   61 EFNAIWNYRR DIIASLASEL EIPFWDKELV FVMMLLKDYP KVYWIWNHRL WVLKHYPTSS 120
  121 PKVWQTELAV VNKLLEQDAR NYHGWHYRRI VVGNIESITN KSLDKEEFEY TTIKINNNIS 180
  181 NYSAWHQRVQ IISRMFQKGE VGNQKEYIRT EISYIINAMF TDAEDQSVWF YIKWFIKNDI 240
  241 VC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	18.09691
Match:	1dceA_
Description:	Rab geranylgeranyltransferase alpha-subunit, N-terminal domain; Rab geranylgeranyltransferase alpha-subunit, insert domain; Rab geranylgeranyltransferase alpha-subunit, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein prenyltransferase activity	14.5503734940473	bayes_pls_golite062009
Rab geranylgeranyltransferase activity	13.1624958019148	bayes_pls_golite062009
protein geranylgeranyltransferase activity	13.1460127219249	bayes_pls_golite062009
prenyltransferase activity	12.4552179391942	bayes_pls_golite062009
protein farnesyltransferase activity	5.75066035906508	bayes_pls_golite062009
CAAX-protein geranylgeranyltransferase activity	3.82151622786875	bayes_pls_golite062009
transferase activity	1.86754243570948	bayes_pls_golite062009
binding	1.29714843812125	bayes_pls_golite062009
catalytic activity	0.874200184943744	bayes_pls_golite062009
protein binding	0.439760416772506	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [243-327]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTLDEQEYLK MLKDLRENIL LINNDEIEFS GKQNIWCLKI LLVLEDILEE KEALTERSSE  60
   61 QYLVQLIDAD PLRKNRYLHL LEQHK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	6.69897
Match:	1kt1A_
Description:	FKBP51, C-terminal domain; FKBP51, N-terminal domains
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: