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View Structure Prediction Details

Protein: GPB2
Organism: Saccharomyces cerevisiae
Length: 880 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GPB2.

Description E-value Query
Range
Subject
Range
GPB1 - Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby incre...
GPB1_YEAST - Guanine nucleotide-binding protein subunit beta 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / ...
0.0 [47..877] [39..894]
gi|45188286, gi|... - gi|45188286|ref|NP_984509.1| ADR414Cp [Ashbya gossypii ATCC 10895], gi|44983130|gb|AAS52333.1| ADR41...
gi|44983130 - gi|44983130|gb|AAS52333.1| ADR414Cp [Ashbya gossypii ATCC 10895]
0.0 [176..874] [153..775]
gi|46444639, gi|... - gi|68466334|ref|XP_722649.1| hypothetical protein CaO19.4577 [Candida albicans SC5314], gi|68466039|...
orf19.12046, orf... - orf19.4577 CGDID:CAL0002877 Assembly 19, Contig19-10212 (23456, 26767) CDS, translated using codon t...
5.0E-52 [277..425] [210..368]

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Predicted Domain #1
Region A:
Residues: [1-171]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEISSSPWND GGYSPYERNR VAVSPFSSAL EGEERIETSR SLGDHCFEPL PYVTNYLSIF  60
   61 ALFGKEIFGD KGNVSSRNEY LLKKYYSLKK PFVLRHNGHA LKNPDMPLQR NDILQTNFMV 120
  121 DKFLNRTVRS VNFNNFKIIS DMQSKSGRGT KSGTNQNQSA DAIQNICLPS I

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [172-263]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSALPYFQYY RKLLTVNTKE WDILKLHSLW VPKLRKDFKD FSLYGDKNSL KPIDSHYDED  60
   61 NTMKKNLFFE RSPSRQTLDG KGCASKGYDI SS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [264-435]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNMIIPSLFS EDKLPALTYH CSVELNGNIY IFGGLMPCYS YEEDAPMLND FFVDGIKNLP  60
   61 PPLLPQVINN PSMVNNPHLY VASIPSCRFS KPKMGGYIPP PLLCVQGSKL TDRHIFFYGG 120
  121 FEIRTETRGD ENGKYHLKKR LYVNNTGYIL DIMSFKFTKI DIIVQPSKYN AY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [436-671]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTMSSRFGHL QISIDNPNRR ASVHSSSMNE IHKMGSASMK QGSSITSGRL EKAAVLSSLP  60
   61 HNTVHTVIIF GGYRQTGDDR YEAMNDLWKI EIPVIRRGKK GYCKFSETAN AILLTPSEKD 120
  121 KSDWPEERAF SAFSVHGTSL MDRSSLDMRL LNNLKNHFVL KPSYISQDRV VSPKPVFPMM 180
  181 VHGTHQDLFN SGSAAQESPK AGASASSASA ASFDPDMDDN LENYIINPGR KSSSIP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [672-880]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAIGRQRLI LSQEKPVGKT VVLHGGSNGL NVLDDMWLMD LECETWTPIE TFAKADSSED  60
   61 GDEKLDSVNV GLVGHRMESI GRICVCIGGM VQEDVDQFYS ENDDEPPRKR KVDTLPLGGN 120
  121 FLNTIDLSTQ FWEEHKITLS KKAADEDRQD SENEDTNSNI VVGVGGTSLQ CDKSIILIGG 180
  181 LISRRSNVKE IYLHGTITKS IFPSVNPSA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle