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View Structure Prediction Details

Protein: ERO1_ARATH
Organism: Arabidopsis thaliana
Length: 469 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ERO1_ARATH.

Description E-value Query
Range
Subject
Range
gi|50582733, gi|... - gi|50582733|gb|AAT78803.1| putative endoplasmic reticulum oxidoreductin [Oryza sativa (japonica cult...
591.0 [0..13] [457..29]

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Predicted Domain #1
Region A:
Residues: [1-469]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKGAIKEEE SEKKRKTWRW PLATLVVVFL AVAVSSRTNS NVGFFFSDRN SCSCSLQKTG  60
   61 KYKGMIEDCC CDYETVDNLN TEVLNPLLQD LVTTPFFRYY KVKLWCDCPF WPDDGMCRLR 120
  121 DCSVCECPEN EFPEPFKKPF VPGLPSDDLK CQEGKPQGAV DRTIDNRAFR GWVETKNPWT 180
  181 HDDDTDSGEM SYVNLQLNPE RYTGYTGPSA RRIWDSIYSE NCPKYSSGET CPEKKVLYKL 240
  241 ISGLHSSISM HIAADYLLDE SRNQWGQNIE LMYDRILRHP DRVRNMYFTY LFVLRAVTKA 300
  301 TAYLEQAEYD TGNHAEDLKT QSLIKQLLYS PKLQTACPVP FDEAKLWQGQ SGPELKQQIQ 360
  361 KQFRNISALM DCVGCEKCRL WGKLQVQGLG TALKILFSVG NQDIGDQTLQ LQRNEVIALV 420
  421 NLLNRLSESV KMVHDMSPDV ERLMEDQIAK VSAKPARLRR IWDLAVSFW

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 120.0
Match: 1rq1A
Description: Structure of Ero1p, Source of Disulfide Bonds for Oxidative Protein Folding in the Cell
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on sulfur group of donors 3.04541306149882 bayes_pls_golite062009
thiol oxidase activity 1.56067935587779 bayes_pls_golite062009
binding 1.51315006963036 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor 1.31287436426921 bayes_pls_golite062009
protein disulfide oxidoreductase activity 1.25764823859811 bayes_pls_golite062009
unfolded protein binding 1.21113889423637 bayes_pls_golite062009
catalytic activity 1.09506175640279 bayes_pls_golite062009
protein binding 0.524855475418758 bayes_pls_golite062009
disulfide oxidoreductase activity 0.384901602591813 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle