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View Structure Prediction Details

Protein: RHM2_ARATH
Organism: Arabidopsis thaliana
Length: 667 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RHM2_ARATH.

Description E-value Query
Range
Subject
Range
RHM1_ARATH - Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rh...
516.0 [0..5] [667..3]

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Predicted Domain #1
Region A:
Residues: [1-371]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDTTYKPKN ILITGAAGFI ASHVANRLIR NYPDYKIVVL DKLDYCSDLK NLDPSFSSPN  60
   61 FKFVKGDIAS DDLVNYLLIT ENIDTIMHFA AQTHVDNSFG NSFEFTKNNI YGTHVLLEAC 120
  121 KVTGQIRRFI HVSTDEVYGE TDEDAAVGNH EASQLLPTNP YSATKAGAEM LVMAYGRSYG 180
  181 LPVITTRGNN VYGPNQFPEK MIPKFILLAM SGKPLPIHGD GSNVRSYLYC EDVAEAFEVV 240
  241 LHKGEIGHVY NVGTKRERRV IDVARDICKL FGKDPESSIQ FVENRPFNDQ RYFLDDQKLK 300
  301 KLGWQERTNW EDGLKKTMDW YTQNPEWWGD VSGALLPHPR MLMMPGGRLS DGSSEKKDVS 360
  361 SNTVQTFTVV T

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 98.522879
Match: 1g1aA
Description: dTDP-glucose 4,6-dehydratase (RmlB)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
UDP-glucose 4-epimerase activity 2.13934644118967 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
steroid dehydrogenase activity 1.75109362865449 bayes_pls_golite062009
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.55012034958204 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.03956654822048 bayes_pls_golite062009
nucleic acid binding 0.868888700854563 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.82673050487418 bayes_pls_golite062009
DNA binding 0.790382977752475 bayes_pls_golite062009
binding 0.784517759335365 bayes_pls_golite062009
transcription regulator activity 0.613310508772122 bayes_pls_golite062009
transcription factor activity 0.11102650759187 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [372-667]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKNGDSGDKA SLKFLIYGKT GWLGGLLGKL CEKQGITYEY GKGRLEDRAS LVADIRSIKP  60
   61 THVFNAAGLT GRPNVDWCES HKPETIRVNV AGTLTLADVC RENDLLMMNF ATGCIFEYDA 120
  121 THPEGSGIGF KEEDKPNFFG SFYSKTKAMV EELLREFDNV CTLRVRMPIS SDLNNPRNFI 180
  181 TKISRYNKVV DIPNSMTVLD ELLPISIEMA KRNLRGIWNF TNPGVVSHNE ILEMYKNYIE 240
  241 PGFKWSNFTV EEQAKVIVAA RSNNEMDGSK LSKEFPEMLS IKESLLKYVF EPNKRT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.39794
Match: 2c59A
Description: gdp-mannose-3', 5' -epimerase (arabidopsis thaliana), with gdp-alpha-d-mannose and gdp-beta-l-galactose bound in the active site.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
UDP-glucose 4-epimerase activity 2.13934644118967 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
steroid dehydrogenase activity 1.75109362865449 bayes_pls_golite062009
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.55012034958204 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.03956654822048 bayes_pls_golite062009
nucleic acid binding 0.868888700854563 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.82673050487418 bayes_pls_golite062009
DNA binding 0.790382977752475 bayes_pls_golite062009
binding 0.784517759335365 bayes_pls_golite062009
transcription regulator activity 0.613310508772122 bayes_pls_golite062009
transcription factor activity 0.11102650759187 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle