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View Structure Prediction Details

Protein: MCA8_ARATH
Organism: Arabidopsis thaliana
Length: 381 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MCA8_ARATH.

Description E-value Query
Range
Subject
Range
gi|51968550 - gi|51968550|dbj|BAD42967.1| hypothetical protein [Arabidopsis thaliana]
334.0 [0..1] [381..1]

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Predicted Domain #1
Region A:
Residues: [1-145]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKKALLIGI NYPGTAVELR GCVNDVHRMQ KCLIELYGFA NKDIVIMIDT DKSCIQPTGK  60
   61 NICDELDNLI ASGQSGDFLV FHYSGHGTRI PPGIEDSEDP TGFDECITPC DMNLIKDQQF 120
  121 REMVSRVKEG CQLTIISDSC HSGGL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.0
Match: 1rwkA
Description: Crystal structure of human caspase-1 in complex with 3-(2-mercapto-acetylamino)-4-oxo-pentanoic acid
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [146-381]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IQEVKEQIGE SHMKPVDKVK EQIEESHMKQ PKLGIASYFL NIVMNLLATC GVSKSQRDRG  60
   61 GGEESFRGEI ELEKDETLDI KTRYLPFESY LSLLKEQTGQ TNIEPVRIRQ TLLKLFGEDP 120
  121 SPNRQRGLSD LGNCEVDAGD SGASRLNAVT DNGILLSGCQ TDQRSEDVYV TRTGKAYGAF 180
  181 SDAIQMILSA PRKDKKKITN KELVSEARVF LKKRGYSQRP GLYCHDRFVD KPFICY

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.05
Match: 1jxqA
Description: Caspase-9
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.446816200197746 bayes_pls_golite062009
binding 0.128865592323915 bayes_pls_golite062009
hydrolase activity 0.00345801703057891 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle