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View Structure Prediction Details

Protein: gi|7594553, gi|1...
Organism: Arabidopsis thaliana
Length: 1531 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7594553, gi|1....

Description E-value Query
Range
Subject
Range
DCL3A_ORYSJ - Endoribonuclease Dicer homolog 3a OS=Oryza sativa subsp. japonica GN=DCL3A PE=2 SV=1
885.0 [0..37] [1524..25]

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Predicted Domain #1
Region A:
Residues: [1-562]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHSSLEPEKM EEGGGSNSLK RKFSEIDGDQ NLDSVSSPMM TDSNGSYELK VYEVAKNRNI  60
   61 IAVLGTGIDK SEITKRLIKA MGSSDTDKRL IIFLAPTVNL QCCEIRALVN LKVEEYFGAK 120
  121 GVDKWTSQRW DEEFSKHDVL VMTPQILLDV LRSAFLKLEM VCLLIIDECH HTTGNHPYAK 180
  181 LMKIFNPEER EGVEKFATTV KEGPILYNPS PSCSLELKEK LETSHLKFDA SLRRLQELGK 240
  241 DSFLNMDNKF ETYQKRLSID YREILHCLDN LGLICAHLAA EVCLEKISDT KEESETYKEC 300
  301 SMVCKEFLED ILSTIGVYLP QDDKSLVDLQ QNHLSAVISG HVSPKLKELF HLLDSFRGDK 360
  361 QKQCLILVER IITAKVIERF VKKEASLAYL NVLYLTENNP STNVSAQKMQ IEIPDLFQHG 420
  421 KVNLLFITDV VEEGFQVPDC SCMVCFDLPK TMCSYSQSQK HAKQSNSKSI MFLERGNPKQ 480
  481 RDHLHDLMRR EVLIQDPEAP NLKSCPPPVK NGHGVKEIGS MVIPDSNITV SEEAASTQTM 540
  541 SDPPSRNEQL PPCKKLRLDN NL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.154902
Match: 1z3iX
Description: Structure of the SWI2/SNF2 chromatin remodeling domain of eukaryotic Rad54
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.37148167194523 bayes_pls_golite062009
binding 0.712909626033412 bayes_pls_golite062009
hydrolase activity 0.42374852534029 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [563-608]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQSNGKEKVA SSKSKSSSSA AGSKKRKELH GTTCANALSG TWGENI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.522879
Match: 1oywA
Description: Structure of the RecQ Catalytic Core
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [609-733]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGATFQAYKF DFCCNISGEV YSSFSLLLES TLAEDVGKVE MDLYLVRKLV KASVSPCGQI  60
   61 RLSQEELVKA KYFQQFFFNG MFGKLFVGSK SQGTKREFLL QTDTSSLWHP AFMFLLLPVE 120
  121 TNDLA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [734-1056]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSATIDWSAI NSCASIVEFL KKNSLLDLRD SDGNQCNTSS GQEVLLDDKM EETNLIHFAN  60
   61 ASSDKNSLEE LVVIAIHTGR IYSIVEAVSD SSAMSPFEVD ASSGYATYAE YFNKKYGIVL 120
  121 AHPNQPLMKL KQSHHAHNLL VDFNEEMVVK TEPKAGNVRK RKPNIHAHLP PELLARIDVP 180
  181 RAVLKSIYLL PSVMHRLESL MLASQLREEI DCSIDNFSIS STSILEAVTT LTCPESFSME 240
  241 RLELLGDSVL KYVASCHLFL KYPDKDEGQL SRQRQSIISN SNLHRLTTSR KLQGYIRNGA 300
  301 FEPRRWTAPG QFSLFPVPCK CGI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.39794
Match: 2fflA
Description: Crystal Structure of Dicer from Giardia intestinalis
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [1057-1143]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTREVPLDPK FFTENMTIKI GKSCDMGHRW VVSKSVSDCA EALIGAYYVS GGLSASLHMM  60
   61 KWLGIDVDFD PNLVVEAINR VSLRCYI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1144-1383]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKEDELIELE RKIQHEFSAK FLLKEAITHS SLRESYSYER LEFLGDSVLD FLITRHLFNT  60
   61 YEQTGPGEMT DLRSACVNNE NFAQVAVKNN LHTHLQRCAT VLETQINDYL MSFQKPDETG 120
  121 RSIPSIQGPK ALGDVVESIA GALLIDTRLD LDQVWRVFEP LLSPLVTPDK LQLPPYRELN 180
  181 ELCDSLGYFF RVKCSNDGVK AQATIQLQLD DVLLTGDGSE QTNKLALGKA ASHLLTQLEK 240
  241 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.0
Match: 1o0wA
Description: RNase III endonuclease catalytic domain; RNase III, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.103878681691 bayes_pls_golite062009
endoribonuclease activity 2.02847548000256 bayes_pls_golite062009
endonuclease activity 1.52328576888271 bayes_pls_golite062009
binding 1.36306903445995 bayes_pls_golite062009
nucleic acid binding 1.33734225890407 bayes_pls_golite062009
double-stranded RNA binding 0.80785216315429 bayes_pls_golite062009
catalytic activity 0.328884095744829 bayes_pls_golite062009
protein binding 0.018276859224266 bayes_pls_golite062009

Predicted Domain #7
Region A:
Residues: [1384-1531]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNISRKTSLG DNQSSMDVNL ACNHSDRETL TSETTEIQSI VIPFIGPINM KKGGPRGTLH  60
   61 EFCKKHLWPM PTFDTSEEKS RTPFEFIDGG EKRTSFSSFT STITLRIPNR EAVMYAGEAR 120
  121 PDKKSSFDSA VVELLYELER RKIVIIQK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.045757
Match: 1qu6A
Description: dsRNA-dependent protein kinase pkr
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.103878681691 bayes_pls_golite062009
binding 1.36306903445995 bayes_pls_golite062009
nucleic acid binding 1.33734225890407 bayes_pls_golite062009
double-stranded RNA binding 0.80785216315429 bayes_pls_golite062009
catalytic activity 0.328884095744829 bayes_pls_golite062009
protein binding 0.018276859224266 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle