YRC Public Data Repository - Protein Structure Prediction

Protein:	NEN3_ARATH
Organism:	Arabidopsis thaliana
Length:	506 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NEN3_ARATH.

Description	E-value	Query Range	Subject Range
NEN2_ARATH - Protein NEN2 OS=Arabidopsis thaliana GN=NEN2 PE=2 SV=1	359.0	[0..1]	[502..4]
gi\|37534222, gi\|... - gi\|37534222\|ref\|NP_921413.1\| putative exonuclease [Oryza sativa (japonica cultivar-group)], gi\|31432...	358.0	[0..11]	[502..28]
gi\|75760399, gi\|... - gi\|75760399\|ref\|ZP_00740443.1\| ATP-dependent helicase, DinG family [Bacillus thuringiensis serovar i...	280.0	[0..11]	[423..3]
gi\|42736665, gi\|... - gi\|42780745\|ref\|NP_977992.1\| bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsi...	280.0	[0..11]	[465..3]
gi\|49477263, gi\|... - gi\|49477263\|ref\|YP_035758.1\| bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsi... gi\|218902753, gi... - gi\|218902753\|ref\|YP_002450587.1\| putative DnaQ family exonuclease/DinG family helicase [Bacillus cer... gi\|196033564, gi... - gi\|196033564\|ref\|ZP_03100976.1\| putative DnaQ family exonuclease/DinG family helicase [Bacillus cere...	279.0	[0..11]	[465..3]
gi\|51977275, gi\|... - gi\|52143806\|ref\|YP_083022.1\| bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsi...	278.0	[0..11]	[465..3]
gi\|49178396, gi\|... - gi\|49184469\|ref\|YP_027721.1\| bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsi... gi\|47526838, gi\|... - gi\|47526838\|ref\|YP_018187.1\| bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsi... gi\|30261638, gi\|... - gi\|30261638\|ref\|NP_844015.1\| bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsi... gi\|177650486, gi... - gi\|177650486\|ref\|ZP_02933453.1\| putative DnaQ family exonuclease/DinG family helicase [Bacillus anth... gi\|190568647, gi... - gi\|190568647\|ref\|ZP_03021552.1\| putative DnaQ family exonuclease/DinG family helicase [Bacillus anth... gi\|167639095, gi... - gi\|167639095\|ref\|ZP_02397368.1\| putative DnaQ family exonuclease/DinG family helicase [Bacillus anth... gi\|170706543, gi... - gi\|170706543\|ref\|ZP_02897003.1\| putative DnaQ family exonuclease/DinG family helicase [Bacillus anth... gi\|165869397, gi... - gi\|165869397\|ref\|ZP_02214056.1\| putative DnaQ family exonuclease/DinG family helicase [Bacillus anth... gi\|227006832, gi... - gi\|227815611\|ref\|YP_002815620.1\| putative DnaQ family exonuclease/DinG family helicase [Bacillus ant... gi\|254759665 - gi\|254759665\|ref\|ZP_05211689.1\| bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit e... gi\|254755128 - gi\|254755128\|ref\|ZP_05207162.1\| bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit e... gi\|254734478 - gi\|254734478\|ref\|ZP_05192190.1\| bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit e... gi\|229266641, gi... - gi\|229602233\|ref\|YP_002866045.1\| putative DnaQ family exonuclease/DinG family helicase [Bacillus ant...	277.0	[0..11]	[465..3]
gi\|21399459, gi\|... - gi\|65318908\|ref\|ZP_00391867.1\| COG1199: Rad3-related DNA helicases [Bacillus anthracis str. A2012], ...	276.0	[0..11]	[465..3]

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Predicted Domain #1

Region A:
Residues: [1-421]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASSLGGDER SEIAFFDLET AVPTKSGEPF AILEFGAILV CPRRLEELYS YSTLVRPTDL  60
   61 SLISTLTKRR SGITRDGVLS AHTFSEIADK VYDILHGRIW AGHNIIRFDC VRIREAFAEI 120
  121 GLSPPEPKAT IDSLSLLSQK FGKRAGDMKM ASLATYFGLG DQAHRSLDDV RMNLEVVKYC 180
  181 ATVLFLESSV PDILTDMSWF SPRKSPRTRS NGKLVANGVR ESSTSSSSSP KTDPSSSSVD 240
  241 ATIVKNHPIV SLLTECSESD ASSYDIEDPI DITTLIGKLR IGTLQTDAAE EAKTVRQQDE 300
  301 SPPSPDSDAK DESFLGVNEV SVSSIRASLV PFYRGSLRMK LFHNDTPLHL CWHSLKVRFG 360
  361 ISRKFVDHAG RPKLNIIVDA PLDLCKILDA VDAAAHNLPT DSSTNSDWRP TVIRKEGFAN 420
  421 Y

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.30103
Match:	1fxxA
Description:	Exonuclease I
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [422-506]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTARLHISSE SNGDDTLCGT QVYQKEEPLG TNQKLDVSSD NLEKLESALL PGTLVDAFFS  60
   61 LEPYSYQQMA GIRLAVKKLV ILLKK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.658	d.192.1	YlxR-like
View	Download	0.640	d.94.1	HPr-like
View	Download	0.595	c.47.1	Thioredoxin-like
View	Download	0.595	c.47.1	Thioredoxin-like
View	Download	0.514	d.94.1	HPr-like
View	Download	0.490	a.3.1	Cytochrome c
View	Download	0.476	d.192.1	YlxR-like
View	Download	0.440	a.4.1	Homeodomain-like
View	Download	0.277	a.74.1	Cyclin-like
View	Download	0.273	a.23.1	HSC20 (HSCB), C-terminal oligomerisation domain
View	Download	0.265	d.74.1	Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH)
View	Download	0.264	a.7.8	GAT domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits