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View Structure Prediction Details

Protein: C7101_ARATH
Organism: Arabidopsis thaliana
Length: 495 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for C7101_ARATH.

Description E-value Query
Range
Subject
Range
CP2CK_MACFA - Cytochrome P450 2C20 OS=Macaca fascicularis GN=CYP2C20 PE=2 SV=1
378.0 [0..12] [486..4]

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Predicted Domain #1
Region A:
Residues: [1-495]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVFSVSIFAS LAPYLISAFL LFLLVEQLSY LFKKRNIPGP FFVPPIIGNA VALVRDPTSF  60
   61 WDKQSSTANI SGLSANYLIG KFIVYIRDTE LSHQIFSNVR PDAFHLIGHP FGKKLFGDHN 120
  121 LIYMFGEDHK SVRRQLAPNF TPKALSTYSA LQQLVILRHL RQWEGSTSGG SRPVSLRQLV 180
  181 RELNLETSQT VFVGPYLDKE AKNRFRTDYN LFNLGSMALP IDLPGFAFGE ARRAVKRLGE 240
  241 TLGICAGKSK ARMAAGEEPA CLIDFWMQAI VAENPQPPHS GDEEIGGLLF DFLFAAQDAS 300
  301 TSSLLWAVTL LDSEPEVLNR VREEVAKIWS PESNALITVD QLAEMKYTRS VAREVIRYRP 360
  361 PATMVPHVAA IDFPLTETYT IPKGTIVFPS VFDSSFQGFT EPDRFDPDRF SETRQEDQVF 420
  421 KRNFLAFGWG PHQCVGQRYA LNHLVLFIAM FSSLLDFKRL RSDGCDEIVY CPTISPKDGC 480
  481 TVFLSRRVAK YPNFS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 101.0
Match: 1pq2A
Description: Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
monooxygenase activity 5.57229509004705 bayes_pls_golite062009
steroid hydroxylase activity 5.04794778387361 bayes_pls_golite062009
retinoic acid 4-hydroxylase activity 3.76307535769621 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3.68151610133025 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 3.47932403870887 bayes_pls_golite062009
retinoic acid binding 3.04897926497756 bayes_pls_golite062009
sterol 14-demethylase activity 2.94610675710811 bayes_pls_golite062009
retinoid binding 2.60220937953757 bayes_pls_golite062009
demethylase activity 2.49146495571604 bayes_pls_golite062009
isoprenoid binding 2.47826119804163 bayes_pls_golite062009
oxysterol 7-alpha-hydroxylase activity 2.36480328243514 bayes_pls_golite062009
arachidonic acid monooxygenase activity 2.35162461983176 bayes_pls_golite062009
electron carrier activity 1.48516712188486 bayes_pls_golite062009
binding 1.2866152532988 bayes_pls_golite062009
fatty acid (omega-1)-hydroxylase activity 0.979631262400031 bayes_pls_golite062009
arachidonic acid epoxygenase activity 0.75181432044872 bayes_pls_golite062009
catalytic activity 0.608111453189583 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 0.33710488712754 bayes_pls_golite062009
oxygen binding 0.3117502273138 bayes_pls_golite062009
1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity 0.169431271735966 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle