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View Structure Prediction Details

Protein: IF4G2_ARATH
Organism: Arabidopsis thaliana
Length: 747 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IF4G2_ARATH.

Description E-value Query
Range
Subject
Range
gi|25083638, gi|... - gi|25083638|gb|AAN72098.1| putative eukaryotic initiation factor 4, eIF4 [Arabidopsis thaliana], gi|...
570.0 [0..1] [747..1]

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Predicted Domain #1
Region A:
Residues: [1-121]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQQQGEPSVL SLRPGGGGGK SRLFVPRFSS SSSFDLTNGG SEETPFPVKR ENSGERVRFS  60
   61 REEILQHRES VQVSDEILRR CKEIAVELFG EEQSWGNHAA ESKITNHTQH RHTETDNRDW 120
  121 H

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [122-437]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRSQIPTSGK EWLRDDPREA KSTWQGSGPT PVLIKAEVPW SAKRGALSDK DRVVKSVKGI  60
   61 LNKLTPEKYE LLKGQLIDAG ITSADILKEV IQLIFENAIL QPTFCEMYAL LCFDINGQLP 120
  121 SFPSEEPGGK EITFKRVLLN NCQEAFEGAG KLKEEIRQMT NPDQEMERMD KEKMAKLRTL 180
  181 GNIRLIGELL KQKMVPEKIV HHIVQELLGD DTKACPAEGD VEALCQFFIT IGKQLDDSPR 240
  241 SRGINDTYFG RLKELARHPQ LELRLRFMVQ NVVDLRANKW VPRREEVKAK KINEIHSEAE 300
  301 RNLGMRPGAM ASMRNN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.39794
Match: 1hu3A
Description: Eukaryotic initiation factor eIF4G
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.373576425899935 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [438-563]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNNRAAVSGA ADGMGLGNIL GRPGTGGMMP GMPGTRVMPM DEDGWEMART RSMPRGNRQT  60
   61 VQQPRFQPPP AINKSLSVNS RLLPQGSGGL LNGGGRPSPL LQGNGSSSAP QASKPIPTVE 120
  121 KPQPRS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.08
Match: 2j63A
Description: No description for 2j63A was found.

Predicted Domain #4
Region A:
Residues: [564-747]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPQPQPQAAP LANSLNAGEL ERKTKSLLEE YFSIRLVDEA LQCVEELKSP SYHPELVKET  60
   61 ISLGLEKNPP LVEPIAKLLK HLISKNVLTS KDLGAGCLLY GSMLDDIGID LPKAPNSFGE 120
  121 FLGELVSAKV LDFELVRDVL KKMEDEWFRK TVLNAVIKSV RECPSGQSVL DSQAVEVEAC 180
  181 QSLL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.0
Match: 1ug3A
Description: C-terminal portion of human eIF4GI
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle