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View Structure Prediction Details

Protein: CP511_ARATH
Organism: Arabidopsis thaliana
Length: 488 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CP511_ARATH.

Description E-value Query
Range
Subject
Range
CYP2C8 - cytochrome P450, family 2, subfamily C, polypeptide 8
363.0 [0..14] [484..4]

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Predicted Domain #1
Region A:
Residues: [1-488]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELDSENKLL KTGLVIVATL VIAKLIFSFF TSDSKKKRLP PTLKAWPPLV GSLIKFLKGP  60
   61 IIMLREEYPK LGSVFTVNLV HKKITFLIGP EVSAHFFKAS ESDLSQQEVY QFNVPTFGPG 120
  121 VVFDVDYSVR QEQFRFFTEA LRVNKLKGYV DMMVTEAEDY FSKWGESGEV DIKVELERLI 180
  181 ILTASRCLLG REVRDQLFDD VSALFHDLDN GMLPISVLFP YLPIPAHRRR DRAREKLSEI 240
  241 FAKIIGSRKR SGKTENDMLQ CFIESKYKDG RQTTESEVTG LLIAALFAGQ HTSSITSTWT 300
  301 GAYLMRYKEY FSAALDEQKN LIAKHGDKID HDILSEMDVL YRCIKEALRL HPPLIMLMRA 360
  361 SHSDFSVTAR DGKTYDIPKG HIVATSPAFA NRLPHIFKDP DTYDPERFSP GREEDKAAGA 420
  421 FSYIAFGGGR HGCLGEPFAY LQIKAIWSHL LRNFELELVS PFPEIDWNAM VVGVKGNVMV 480
  481 RYKRRQLS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.221849
Match: 1e9xA
Description: Cytochrome p450 14 alpha-sterol demethylase (cyp51)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
monooxygenase activity 5.57229509004705 bayes_pls_golite062009
steroid hydroxylase activity 5.04794778387361 bayes_pls_golite062009
oxysterol 7-alpha-hydroxylase activity 5.03099580095037 bayes_pls_golite062009
retinoic acid 4-hydroxylase activity 3.76307535769621 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 3.51923259313626 bayes_pls_golite062009
demethylase activity 3.40807632433846 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3.24344797738248 bayes_pls_golite062009
retinoic acid binding 3.04897926497756 bayes_pls_golite062009
sterol 14-demethylase activity 2.94610675710811 bayes_pls_golite062009
retinoid binding 2.60220937953757 bayes_pls_golite062009
isoprenoid binding 2.47826119804163 bayes_pls_golite062009
corticosterone 18-monooxygenase activity 2.39818079128436 bayes_pls_golite062009
steroid 11-beta-monooxygenase activity 2.39818079128436 bayes_pls_golite062009
arachidonic acid monooxygenase activity 2.39688955430367 bayes_pls_golite062009
steroid 7-alpha-hydroxylase activity 2.29989218606587 bayes_pls_golite062009
oxidoreductase activity 2.09151585300316 bayes_pls_golite062009
steroid 17-alpha-monooxygenase activity 2.036553099796 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1.97593187367475 bayes_pls_golite062009
oxygen binding 1.66120675703571 bayes_pls_golite062009
electron carrier activity 1.48516712188486 bayes_pls_golite062009
binding 1.2866152532988 bayes_pls_golite062009
fatty acid (omega-1)-hydroxylase activity 1.02400450548438 bayes_pls_golite062009
arachidonic acid epoxygenase activity 0.79568492499797 bayes_pls_golite062009
catalytic activity 0.608111453189583 bayes_pls_golite062009
1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity 0.169431271735966 bayes_pls_golite062009

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