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View Structure Prediction Details

Protein: RHM3_ARATH
Organism: Arabidopsis thaliana
Length: 664 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RHM3_ARATH.

Description E-value Query
Range
Subject
Range
RHM1_ARATH - Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rh...
522.0 [0..1] [656..1]

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Predicted Domain #1
Region A:
Residues: [1-365]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATYKPKNIL ITGAAGFIAS HVANRLVRSY PDYKIVVLDK LDYCSNLKNL NPSKSSPNFK  60
   61 FVKGDIASAD LVNYLLITEE IDTIMHFAAQ THVDNSFGNS FEFTKNNIYG THVLLEACKV 120
  121 TGQIRRFIHV STDEVYGETD EDASVGNHEA SQLLPTNPYS ATKAGAEMLV MAYGRSYGLP 180
  181 VITTRGNNVY GPNQFPEKLI PKFILLAMNG KPLPIHGDGS NVRSYLYCED VAEAFEVVLH 240
  241 KGEVNHVYNI GTTRERRVID VANDISKLFG IDPDSTIQYV ENRPFNDQRY FLDDQKLKKL 300
  301 GWCERTNWEE GLRKTMEWYT ENPEWWGDVS GALLPHPRML MMPGDRHSDG SDEHKNADGN 360
  361 QTFTV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 100.0
Match: 1g1aA
Description: dTDP-glucose 4,6-dehydratase (RmlB)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
UDP-glucose 4-epimerase activity 2.13934644118967 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
steroid dehydrogenase activity 1.75109362865449 bayes_pls_golite062009
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.55012034958204 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.03956654822048 bayes_pls_golite062009
nucleic acid binding 0.868888700854563 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.82673050487418 bayes_pls_golite062009
DNA binding 0.790382977752475 bayes_pls_golite062009
binding 0.784517759335365 bayes_pls_golite062009
transcription regulator activity 0.613310508772122 bayes_pls_golite062009
transcription factor activity 0.11102650759187 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [366-664]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTPTKAGCSG DKRSLKFLIY GKTGWLGGLL GKLCEKQGIP YEYGKGRLED RASLIADIRS  60
   61 IKPSHVFNAA GLTGRPNVDW CESHKTETIR VNVAGTLTLA DVCRENDLLM MNFATGCIFE 120
  121 YDAAHPEGSG IGFKEEDKPN FTGSFYSKTK AMVEELLREF DNVCTLRVRM PISSDLNNPR 180
  181 NFITKISRYN KVVNIPNSMT ILDELLPISI EMAKRNLRGI WNFTNPGVVS HNEILEMYKS 240
  241 YIEPDFKWSN FNLEEQAKVI VAPRSNNEMD GAKLSKEFPE MLSIKDSLIK YVFEPNKRT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.522879
Match: 2c59A
Description: gdp-mannose-3', 5' -epimerase (arabidopsis thaliana), with gdp-alpha-d-mannose and gdp-beta-l-galactose bound in the active site.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
UDP-glucose 4-epimerase activity 2.13934644118967 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
steroid dehydrogenase activity 1.75109362865449 bayes_pls_golite062009
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.55012034958204 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.03956654822048 bayes_pls_golite062009
nucleic acid binding 0.868888700854563 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.82673050487418 bayes_pls_golite062009
DNA binding 0.790382977752475 bayes_pls_golite062009
binding 0.784517759335365 bayes_pls_golite062009
transcription regulator activity 0.613310508772122 bayes_pls_golite062009
transcription factor activity 0.11102650759187 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle