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View Structure Prediction Details

Protein: AGO4_ARATH
Organism: Arabidopsis thaliana
Length: 924 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AGO4_ARATH.

Description E-value Query
Range
Subject
Range
gi|73977123 - gi|73977123|ref|XP_532563.2| PREDICTED: similar to eukaryotic translation initiation factor 2C, 1 [C...
888.0 [0..4] [923..149]
gi|84688912 - gi|84688912|gb|ABC61505.1| AGO4-2 [Nicotiana benthamiana]
883.0 [0..39] [924..25]
gi|62649646 - gi|62649646|ref|XP_233544.3| PREDICTED: similar to eukaryotic translation initiation factor 2C, 1 [R...
881.0 [0..3] [923..153]
gi|92897724, gi|... - gi|92897724|gb|ABE93839.1| Argonaute and Dicer protein, PAZ [Medicago truncatula], gi|92874347|gb|AB...
877.0 [0..33] [923..17]
AGO4B_ORYSJ - Protein argonaute 4B OS=Oryza sativa subsp. japonica GN=AGO4B PE=2 SV=1
874.0 [0..48] [924..37]
gi|116308832, gi... - gi|218194291|gb|EEC76718.1| hypothetical protein OsI_14737 [Oryza sativa Indica Group], gi|116308832...
873.0 [0..48] [924..37]
gi|66792511 - gi|66792511|gb|AAH96465.1| Eif2c2 protein [Mus musculus]
870.0 [0..14] [923..7]

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Predicted Domain #1
Region A:
Residues: [1-99]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSTNGNGAD LESANGANGS GVTEALPPPP PVIPPNVEPV RVKTELAEKK GPVRVPMARK  60
   61 GFGTRGQKIP LLTNHFKVDV ANLQGHFFHY SVALFYDDG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [100-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RPVEQKGVGR KILDKVHQTY HSDLDGKEFA YDGEKTLFTY GALPSNKMDF SVVLEEVSAT  60
   61 RANGNGSPNG NESPSDGDRK RLRRPNRSKN FRVEISYAAK IPLQALANAM RGQESENSQE 120
  121 AIRVLDIILR QHAARQGCLL VRQSFFHNDP TNCEPVGGNI LGCRGFHSSF RTTQGGMSLN 180
  181 MD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [282-480]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTTTMIIKPG PVVDFLIANQ NARDPYSIDW SKAKRTLKNL RVKVSPSGQE FKITGLSDKP  60
   61 CREQTFELKK RNPNENGEFE TTEVTVADYF RDTRHIDLQY SADLPCINVG KPKRPTYIPL 120
  121 ELCALVPLQR YTKALTTFQR SALVEKSRQK PQERMTVLSK ALKVSNYDAE PLLRSCGISI 180
  181 SSNFTQVEGR VLPAPKLKM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.69897
Match: 1r4kA
Description: Solution Structure of the Drosophila Argonaute 1 PAZ Domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [481-924]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GCGSETFPRN GRWNFNNKEF VEPTKIQRWV VVNFSARCNV RQVVDDLIKI GGSKGIEIAS  60
   61 PFQVFEEGNQ FRRAPPMIRV ENMFKDIQSK LPGVPQFILC VLPDKKNSDL YGPWKKKNLT 120
  121 EFGIVTQCMA PTRQPNDQYL TNLLLKINAK LGGLNSMLSV ERTPAFTVIS KVPTIILGMD 180
  181 VSHGSPGQSD VPSIAAVVSS REWPLISKYR ASVRTQPSKA EMIESLVKKN GTEDDGIIKE 240
  241 LLVDFYTSSN KRKPEHIIIF RDGVSESQFN QVLNIELDQI IEACKLLDAN WNPKFLLLVA 300
  301 QKNHHTKFFQ PTSPENVPPG TIIDNKICHP KNNDFYLCAH AGMIGTTRPT HYHVLYDEIG 360
  361 FSADELQELV HSLSYVYQRS TSAISVVAPI CYAHLAAAQL GTFMKFEDQS ETSSSHGGIT 420
  421 APGPISVAQL PRLKDNVANS MFFC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.09691
Match: 1w9hA
Description: The Structure of a Piwi protein from Archaeoglobus fulgidus.
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle