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View Structure Prediction Details

Protein: TF2H2_ARATH
Organism: Arabidopsis thaliana
Length: 421 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TF2H2_ARATH.

Description E-value Query
Range
Subject
Range
gi|31981225, gi|... - gi|31981225|ref|NP_071294.2| general transcription factor II H, polypeptide 2 [Mus musculus], gi|314...
347.0 [0..17] [415..2]

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Predicted Domain #1
Region A:
Residues: [1-282]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNQRKRSND EREEEDDEDA EGIGEWERAY VDDRSWEELQ EDESGLLRPI DNSAIYHAQY  60
   61 RRRLRMLSAA AAGTRIQKGL IRYLYIVIDF SRAAAEMDFR PSRMAIMAKH VEAFIREFFD 120
  121 QNPLSQIGLV SIKNGVAHTL TDLGGSPETH IKALMGKLEA LGDSSLQNAL ELVHEHLNQV 180
  181 PSYGHREVLI LYSALCTCDP GDIMETIQKC KKSKLRCSVI GLSAEMFICK HLCQETGGLY 240
  241 SVAVDEVHLK DLLLEHAPPP PAIAEFAIAN LIKMGFPQRA AE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.522879
Match: 2ok5A
Description: No description for 2ok5A was found.

Predicted functions:

Term Confidence Notes
binding 2.78081530457495 bayes_pls_golite062009
protein binding 1.87564165872234 bayes_pls_golite062009
DNA binding 1.67175195853604 bayes_pls_golite062009
nucleic acid binding 1.66804415166051 bayes_pls_golite062009
cell surface binding 1.100737691234 bayes_pls_golite062009
eukaryotic cell surface binding 0.75976840299626 bayes_pls_golite062009
hydrolase activity 0.713727944323346 bayes_pls_golite062009
protein complex binding 0.68878168136573 bayes_pls_golite062009
receptor activity 0.537407856490475 bayes_pls_golite062009
structure-specific DNA binding 0.450760554291027 bayes_pls_golite062009
transmembrane receptor activity 0.414030020499752 bayes_pls_golite062009
protein heterodimerization activity 0.32921284315242 bayes_pls_golite062009
catalytic activity 0.252597265474331 bayes_pls_golite062009
heparin binding 0.0497639742848703 bayes_pls_golite062009
complement binding 0.0415669963240149 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [283-421]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSMAICSCHK EVKIGAGYMC PRCKARVCDL PTECTICGLT LVSSPHLARS YHHLFPIAPF  60
   61 DEVPALSSLN DNRRKLGKSC FGCQQSLIGA GNKPVPCVTC RKCKHYFCLD CDIYIHESLH 120
  121 NCPGCESIHR PKSVSLMEE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.09691
Match: 1z60A
Description: Solution structure of the carboxy-terminal domain of human TFIIH P44 subunit
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle