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View Structure Prediction Details

Protein: ORP1B_ARATH
Organism: Arabidopsis thaliana
Length: 489 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ORP1B_ARATH.

Description E-value Query
Range
Subject
Range
ORP1A_ARATH - Oxysterol-binding protein-related protein 1A OS=Arabidopsis thaliana GN=ORP1A PE=2 SV=1
554.0 [0..35] [489..300]

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Predicted Domain #1
Region A:
Residues: [1-80]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEARVISCTT FGDNKVVKIA VLNHQAITKY KAGENETTVV VSDDTCPEKD VKEIKKFCEK  60
   61 LGYVYEGRLS EEYTQTNTGP 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.747 N/A N/A b.71.1 Glycosyl hydrolase domain
View Download 0.721 N/A N/A b.71.1 Glycosyl hydrolase domain
View Download 0.715 N/A N/A d.79.3 L30e-like
View Download 0.683 N/A N/A d.79.3 L30e-like
View Download 0.672 N/A N/A d.58.18 Regulatory domain in the aminoacid metabolism

Predicted Domain #2
Region A:
Residues: [81-489]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDDWITNGFE SDDDVDPSIK TIGFNYPHVN RRNKLPDPVE KEKSVSLWSM IKDNIGKDLT  60
   61 KVCLPVYFNE PLSSLQKCFE DLEYSYLLDQ ASEWGKRGNN LMRILNVAAF AVSGYASTKG 120
  121 RICKPFNPML GETYEADYPD KGLRFFSEKV SHHPMIVACH CDGTGWKFWG DSNLKSKFWG 180
  181 RSIQLDPIGL LTLQFDDGEI VQWSKVTTSI YNLILGKLYC DHYGTMLIEG NGEYSCKLKF 240
  241 KKQSMMDRNP HQVQGIVEDK NGKTVAKLFG KWDESMYYVM VNQGKESESH LLWKRNKPLE 300
  301 NPTKYNLTRF GITLNELTPD LKEMLPPTDS RLRPDQRYLE KGEFEMGNRE KLRLEQRQRQ 360
  361 AREKQERGWK PTWFSKEKGS ETYRYIGGYW EARDSGRWDD CPDIFGQVH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 70.69897
Match: 1zhtA
Description: Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
sterol binding 3.12877992228795 bayes_pls_golite062009
steroid binding 2.54679035876403 bayes_pls_golite062009
binding 1.67154210149282 bayes_pls_golite062009
lipid binding 1.46539100663772 bayes_pls_golite062009
oxysterol binding 1.1738554488982 bayes_pls_golite062009
phospholipid binding 0.0867097353003303 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle