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View Structure Prediction Details

Protein: TRXM4_ARATH
Organism: Arabidopsis thaliana
Length: 193 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRXM4_ARATH.

Description E-value Query
Range
Subject
Range
gi|6539614 - gi|6539614|gb|AAF15951.1|AF095752_1 thioredoxin m4 [Arabidopsis thaliana]
177.0 [0..1] [193..1]

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Predicted Domain #1
Region A:
Residues: [1-85]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASLLDSVTV TRVFSLPIAA SVSSSSAAPS VSRRRISPAR FLEFRGLKSS RSLVTQSASL  60
   61 GANRRTRIAR GGRIACEAQD TTAAA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.676 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.457 a.4.5 "Winged helix" DNA-binding domain
View Download 0.420 d.74.2 C-terminal domain of arginine repressor
View Download 0.415 a.6.1 Putative DNA-binding domain
View Download 0.399 d.15.8 Translation initiation factor IF3, N-terminal domain

Predicted Domain #2
Region A:
Residues: [86-193]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VEVPNLSDSE WQTKVLESDV PVLVEFWAPW CGPCRMIHPI VDQLAKDFAG KFKFYKINTD  60
   61 ESPNTANRYG IRSVPTVIIF KGGEKKDSII GAVPRETLEK TIERFLVE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.0
Match: 1fb0A
Description: Thioredoxin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
antioxidant activity 3.8464796631544 bayes_pls_golite062009
peroxidase activity 3.43831566988273 bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor 3.43831566988273 bayes_pls_golite062009
oxidoreductase activity 2.63737118711715 bayes_pls_golite062009
glutathione peroxidase activity 2.56524997297011 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 2.23310780102446 bayes_pls_golite062009
peroxiredoxin activity 2.12777217096121 bayes_pls_golite062009
selenium binding 1.97148144306198 bayes_pls_golite062009
thioredoxin peroxidase activity 1.96134566495756 bayes_pls_golite062009
protein disulfide oxidoreductase activity 1.47769936616412 bayes_pls_golite062009
disulfide oxidoreductase activity 1.32811008894503 bayes_pls_golite062009
binding 0.704132579378598 bayes_pls_golite062009
catalytic activity 0.129588295266429 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 0.0801269279614203 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle