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View Structure Prediction Details

Protein: LOX1_ARATH
Organism: Arabidopsis thaliana
Length: 859 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LOX1_ARATH.

Description E-value Query
Range
Subject
Range
gi|16904543 - gi|16904543|emb|CAD10740.1| lipoxygenase [Corylus avellana]
1392.0 [0..1] [859..1]

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Predicted Domain #1
Region A:
Residues: [1-859]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFGELRDLLT GGGNETTTKK VKGTVVLMKK NVLDFNDFNA SFLDRLHEFL GNKITLRLVS  60
   61 SDVTDSENGS KGKLGKAAHL EDWITTITSL TAGESAFKVT FDYETDFGYP GAFLIRNSHF 120
  121 SEFLLKSLTL EDVPGHGRVH YICNSWIYPA KHYTTDRVFF SNKTYLPHET PATLLKYREE 180
  181 ELVSLRGTGE GELKEWDRVY DYAYYNDLGV PPKNPRPVLG GTQEYPYPRR GRTGRKPTKE 240
  241 DPQTESRLPI TSSLDIYVPR DERFGHLKMS DFLAYALKAI AQFIQPALEA VFDDTPKEFD 300
  301 SFEDVLKIYE EGIDLPNQAL IDSIVKNIPL EMLKEIFRTD GQKFLKFPVP QVIKEDKTAW 360
  361 RTDEEFAREM LAGLNPVVIQ LLKEFPPKSK LDSESYGNQN STITKSHIEH NLDGLTVEEA 420
  421 LEKERLFILD HHDTLMPYLG RVNTTTTKTY ASRTLLFLKD DGTLKPLVIE LSLPHPNGDK 480
  481 FGAVSEVYTP GEGVYDSLWQ LAKAFVGVND SGNHQLISHW MQTHASIEPF VIATNRQLSV 540
  541 LHPVFKLLEP HFRDTMNINA LARQILINGG GIFEITVFPS KYAMEMSSFI YKNHWTFPDQ 600
  601 ALPAELKKRG MAVEDPEAPH GLRLRIKDYP YAVDGLEVWY AIESWVRDYI FLFYKIEEDI 660
  661 QTDTELQAWW KEVREEGHGD KKSEPWWPKM QTREELVESC TIIIWVASAL HAAVNFGQYP 720
  721 VAGYLPNRPT ISRQYMPKEN TPEFEELEKN PDKVFLKTIT AQLQTLLGIS LIEILSTHSS 780
  781 DEVYLGQRDS KEWAAEKEAL EAFEKFGEKV KEIEKNIDER NDDETLKNRT GLVKMPYTLL 840
  841 FPSSEGGVTG RGIPNSVSI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 1hu9A
Description: Lipoxigenase, C-terminal domain; Plant lipoxigenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
arachidonate 12-lipoxygenase activity 2.97198477063857 bayes_pls_golite062009
hepoxilin-epoxide hydrolase activity 2.06608775760905 bayes_pls_golite062009
protein binding 1.53930087292625 bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1.39829306055845 bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1.32313076160919 bayes_pls_golite062009
binding 1.2577136186178 bayes_pls_golite062009
dioxygenase activity 0.515054165229715 bayes_pls_golite062009
arachidonate 15-lipoxygenase activity 0.440928568408097 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle