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View Structure Prediction Details

Protein: EGL1_ARATH
Organism: Arabidopsis thaliana
Length: 596 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EGL1_ARATH.

Description E-value Query
Range
Subject
Range
gi|2335192 - gi|2335192|gb|AAB72192.1| bHLH protein [Arabidopsis thaliana]
517.0 [0..1] [596..1]

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Predicted Domain #1
Region A:
Residues: [1-99]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATGENRTVP DNLKKQLAVS VRNIQWSYGI FWSVSASQPG VLEWGDGYYN GDIKTRKTIQ  60
   61 AAEVKIDQLG LERSEQLREL YESLSLAESS ASGSSQVTR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [100-274]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RASAAALSPE DLTDTEWYYL VCMSFVFNIG EGIPGGALSN GEPIWLCNAE TADSKVFTRS  60
   61 LLAKSASLQT VVCFPFLGGV LEIGTTEHIK EDMNVIQSVK TLFLEAPPYT TISTRSDYQE 120
  121 IFDPLSDDKY TPVFITEAFP TTSTSGFEQE PEDHDSFIND GGASQVQSWQ FVGEE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.01
Match: 1f5mA
Description: Hypothetical protein ykl069wp
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [275-397]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISNCIHQSLN SSDCVSQTFV GTTGRLACDP RKSRIQRLGQ IQEQSNHVNM DDDVHYQGVI  60
   61 STIFKTTHQL ILGPQFQNFD KRSSFTRWKR SSSVKTLGEK SQKMIKKILF EVPLMNKKEE 120
  121 LLP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [398-505]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTPEETGNHA LSEKKRREKL NERFMTLRSI IPSISKIDKV SILDDTIEYL QDLQKRVQEL  60
   61 ESCRESADTE TRITMMKRKK PDDEEERASA NCMNSKRKGS DVNVGEDE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.522879
Match: 1nkpA
Description: Myc prot-oncogene protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.12507195426228 bayes_pls_golite062009
nucleic acid binding 0.43204604575196 bayes_pls_golite062009
DNA binding 0.40884226851256 bayes_pls_golite062009
transcription regulator activity 0.31759335140578 bayes_pls_golite062009
transcription factor activity 0.09721565916723 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [506-596]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PADIGYAGLT DNLRISSLGN EVVIELRCAW REGILLEIMD VISDLNLDSH SVQSSTGDGL  60
   61 LCLTVNCKHK GTKIATTGMI QEALQRVAWI C

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.3
Match: 1zpvA
Description: ACT domain protein from Streptococcus pneumoniae
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.0923752113053079 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle