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View Structure Prediction Details

Protein: CRY2_ARATH
Organism: Arabidopsis thaliana
Length: 612 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CRY2_ARATH.

Description E-value Query
Range
Subject
Range
gi|18026278, gi|... - gi|18026278|gb|AAL16378.1| cryptochrome 2 [Arabidopsis thaliana], gi|18026276|gb|AAL16377.1| cryptoc...
599.0 [0..1] [612..1]

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Predicted Domain #1
Region A:
Residues: [1-536]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKMDKKTIVW FRRDLRIEDN PALAAAAHEG SVFPVFIWCP EEEGQFYPGR ASRWWMKQSL  60
   61 AHLSQSLKAL GSDLTLIKTH NTISAILDCI RVTGATKVVF NHLYDPVSLV RDHTVKEKLV 120
  121 ERGISVQSYN GDLLYEPWEI YCEKGKPFTS FNSYWKKCLD MSIESVMLPP PWRLMPITAA 180
  181 AEAIWACSIE ELGLENEAEK PSNALLTRAW SPGWSNADKL LNEFIEKQLI DYAKNSKKVV 240
  241 GNSTSLLSPY LHFGEISVRH VFQCARMKQI IWARDKNSEG EESADLFLRG IGLREYSRYI 300
  301 CFNFPFTHEQ SLLSHLRFFP WDADVDKFKA WRQGRTGYPL VDAGMRELWA TGWMHNRIRV 360
  361 IVSSFAVKFL LLPWKWGMKY FWDTLLDADL ECDILGWQYI SGSIPDGHEL DRLDNPALQG 420
  421 AKYDPEGEYI RQWLPELARL PTEWIHHPWD APLTVLKASG VELGTNYAKP IVDIDTAREL 480
  481 LAKAISRTRE AQIMIGAAPD EIVADSFEAL GANTIKEPGL CPSVSSNDQQ VPSAVR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 124.0
Match: 1u3cA
Description: Crystal Structure of the PHR domain of Cryptochrome 1 from Arabidopsis thaliana
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
blue light photoreceptor activity 9.1431674572348 bayes_pls_golite062009
photoreceptor activity 8.36697703010092 bayes_pls_golite062009
DNA photolyase activity 5.59238172310626 bayes_pls_golite062009
transcription repressor activity 4.08500855631983 bayes_pls_golite062009
transcription regulator activity 3.49617875539388 bayes_pls_golite062009
nucleic acid binding 2.19167058827256 bayes_pls_golite062009
binding 2.13238451443633 bayes_pls_golite062009
G-protein coupled photoreceptor activity 2.1101484978621 bayes_pls_golite062009
DNA binding 2.05514577638135 bayes_pls_golite062009
deoxyribodipyrimidine photo-lyase activity 2.01343813518186 bayes_pls_golite062009
FAD binding 1.81559602758107 bayes_pls_golite062009
catalytic activity 0.609980967042895 bayes_pls_golite062009
damaged DNA binding 0.5555984473366 bayes_pls_golite062009
protein binding 0.452275661161724 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [537-612]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YNGSKRVKPE EEEERDMKKS RGFDERELFS TAESSSSSSV FFVSQSCSLA SEGKNLEGIQ  60
   61 DSSDQITTSL GKNGCK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle