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View Structure Prediction Details

Protein: C90A1_ARATH
Organism: Arabidopsis thaliana
Length: 472 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for C90A1_ARATH.

Description E-value Query
Range
Subject
Range
gi|73998086 - gi|73998086|ref|XP_859537.1| PREDICTED: similar to Cytochrome P450 2C19 ((R)-limonene 6-monooxygenas...
369.0 [0..3] [467..1]

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Predicted Domain #1
Region A:
Residues: [1-472]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFTAFLLLL SSIAAGFLLL LRRTRYRRMG LPPGSLGLPL IGETFQLIGA YKTENPEPFI  60
   61 DERVARYGSV FMTHLFGEPT IFSADPETNR FVLQNEGKLF ECSYPASICN LLGKHSLLLM 120
  121 KGSLHKRMHS LTMSFANSSI IKDHLMLDID RLVRFNLDSW SSRVLLMEEA KKITFELTVK 180
  181 QLMSFDPGEW SESLRKEYLL VIEGFFSLPL PLFSTTYRKA IQARRKVAEA LTVVVMKRRE 240
  241 EEEEGAERKK DMLAALLAAD DGFSDEEIVD FLVALLVAGY ETTSTIMTLA VKFLTETPLA 300
  301 LAQLKEEHEK IRAMKSDSYS LEWSDYKSMP FTQCVVNETL RVANIIGGVF RRAMTDVEIK 360
  361 GYKIPKGWKV FSSFRAVHLD PNHFKDARTF NPWRWQSNSV TTGPSNVFTP FGGGPRLCPG 420
  421 YELARVALSV FLHRLVTGFS WVPAEQDKLV FFPTTRTQKR YPIFVKRRDF AT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 96.045757
Match: 1pq2A
Description: Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
monooxygenase activity 5.86978331215708 bayes_pls_golite062009
steroid hydroxylase activity 4.96257526704264 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 4.53405878979676 bayes_pls_golite062009
retinoic acid 4-hydroxylase activity 3.76307535769621 bayes_pls_golite062009
retinoic acid binding 3.04897926497756 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1.54326226999739 bayes_pls_golite062009
electron carrier activity 1.48516712188486 bayes_pls_golite062009
binding 1.0760589965579 bayes_pls_golite062009
retinoid binding 0.801772586910166 bayes_pls_golite062009
isoprenoid binding 0.749261239166908 bayes_pls_golite062009
catalytic activity 0.608111453189583 bayes_pls_golite062009
oxygen binding 0.3117502273138 bayes_pls_golite062009
arachidonic acid monooxygenase activity 0.190947703447706 bayes_pls_golite062009
1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity 0.169431271735966 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 0.143379543086271 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle