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View Structure Prediction Details

Protein: C71BU_ARATH
Organism: Arabidopsis thaliana
Length: 498 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for C71BU_ARATH.

Description E-value Query
Range
Subject
Range
gi|115496944, gi... - gi|94574282|gb|AAI16042.1| Cytochrome P450, family 2, subfamily C, polypeptide 18 [Bos taurus], gi|1...
406.0 [0..19] [495..20]

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Predicted Domain #1
Region A:
Residues: [1-498]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMFLGLLFL FPLFFILFKN LLPPRKKLPP GPTGLPLIGN LHQLGRLLHS SLHKLSLEHG  60
   61 PVMLVRWGVV PMAVFSSNEA AKEVLKTHDL ETCNRPKLVA NGLFTHGYKD IGFTQYGEEW 120
  121 REMKKFVGLE LFSPKKHKSF RYIREEEGDL LVKKISNYAQ TQTLVDLRKS LFSYTASIIF 180
  181 REAFGQNFRE CDYINMDKLE ELVQETETNV CSLAFTDFFP RGLGWLVDRI SGQHSRMNIA 240
  241 FSKLTTFFED VIDELLKTKQ LDDHSDLVTA MLDVINRPRK FGSLKITYDH LIAMMSDVVL 300
  301 AGVNAGTVTM IWTMTELTRH PRVMKKLQEE IRATLGPNKE RITEEDLEKV EYLNLVIKES 360
  361 FRLHPPAPLL LPRETMSDIE IQGYHIPKNA HVKINTYAIG RDPKRWTNPE EFNPERFLNT 420
  421 SINYKGQHYE LLPFGAGRRN CPGMTLGITI LELGLLNILY YFDWSLPSGM TIKDIDMEED 480
  481 GALNIAKKVP LQLVPTLP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 110.0
Match: 1pq2A
Description: Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
arachidonic acid monooxygenase activity 6.76823710927794 bayes_pls_golite062009
arachidonic acid epoxygenase activity 4.80764258881036 bayes_pls_golite062009
monooxygenase activity 4.68917162030329 bayes_pls_golite062009
electron carrier activity 4.64931978461551 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3.68151610133025 bayes_pls_golite062009
steroid hydroxylase activity 3.34643016685712 bayes_pls_golite062009
oxygen binding 2.77495508953933 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2.56821164444595 bayes_pls_golite062009
oxidoreductase activity 2.35847923992364 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen 2.15105968497418 bayes_pls_golite062009
binding 1.85787475102988 bayes_pls_golite062009
flavonoid 3'-monooxygenase activity 1.71233606135238 bayes_pls_golite062009
fatty acid (omega-1)-hydroxylase activity 1.65569090470706 bayes_pls_golite062009
demethylase activity 1.32867022434023 bayes_pls_golite062009
ecdysteroid 25-hydroxylase activity 0.89030345144459 bayes_pls_golite062009
catalytic activity 0.608111453189583 bayes_pls_golite062009
testosterone 6-beta-hydroxylase activity 0.38659560844654 bayes_pls_golite062009
sterol 14-demethylase activity 0.26319330575663 bayes_pls_golite062009
arachidonic acid 11,12-epoxygenase activity 0.0888154993183798 bayes_pls_golite062009
oxysterol 7-alpha-hydroxylase activity 0.0096683923835994 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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