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View Structure Prediction Details

Protein: APR2_ARATH
Organism: Arabidopsis thaliana
Length: 454 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for APR2_ARATH.

Description E-value Query
Range
Subject
Range
gi|2098778, gi|2... - gi|21617937|gb|AAM66987.1| 5'-adenylylphosphosulfate reductase, putative [Arabidopsis thaliana], gi|...
367.0 [0..1] [454..1]

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Predicted Domain #1
Region A:
Residues: [1-333]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALAVTSSST AISGSSFSRS GASSESKALQ ICSIRLSDRT HLSQRRYSMK PLNAESHSRS  60
   61 ESWVTRASTL IAPEVEEKGG EVEDFEQLAK KLEDASPLEI MDKALERFGD QIAIAFSGAE 120
  121 DVALIEYARL TGKPFRVFSL DTGRLNPETY RLFDAVEKQY GIRIEYMFPD AVEVQALVRN 180
  181 KGLFSFYEDG HQECCRVRKV RPLRRALKGL KAWITGQRKD QSPGTRSEIP IVQVDPVFEG 240
  241 LDGGVGSLVK WNPLANVEGA DVWNFLRTMD VPVNALHAQG YVSIGCEPCT RPVLPGQHER 300
  301 EGRWWWEDAK AKECGLHKGN IKEEDGAADS KPA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 57.221849
Match: 2goyA
Description: No description for 2goyA was found.

Predicted Domain #2
Region A:
Residues: [334-454]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AVQEIFESNN VVALSKGGVE NLLKLENRKE AWLVVLYAPW CPFCQAMEAS YIELAEKLAG  60
   61 KGVKVAKFRA DGEQKEFAKQ ELQLGSFPTI LLFPKRAPRA IKYPSEHRDV DSLMSFVNLL 120
  121 R

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.69897
Match: 1mekA
Description: HUMAN PROTEIN DISULFIDE ISOMERASE, NMR, 40 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
antioxidant activity 1.78836688224506 bayes_pls_golite062009
peroxidase activity 1.62851025934188 bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor 1.62851025934188 bayes_pls_golite062009
glutathione peroxidase activity 1.08052084417939 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 1.0279404567142 bayes_pls_golite062009
binding 0.704132579378598 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
peroxiredoxin activity 0.366096607480921 bayes_pls_golite062009
glutathione binding 0.2456976890622 bayes_pls_golite062009
transcription regulator activity 0.20838537849107 bayes_pls_golite062009
thioredoxin peroxidase activity 0.163136748643487 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle