YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: alp1
Organism: Schizosaccharomyces pombe
Length: 1107 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for alp1.

Description E-value Query
Range		 Subject
Range
gi|40789011 - gi|40789011|dbj|BAA76832.2| KIAA0988 protein [Homo sapiens]
 714.0 [0..3] [1100..35]
gi|114671149 - gi|114671149|ref|XP_001168814.1| PREDICTED: beta-tubulin cofactor D isoform 3 [Pan troglodytes]
 698.0 [0..3] [1100..17]
gi|109492428 - gi|109492428|ref|XP_001081857.1| PREDICTED: similar to tubulin-specific chaperone d [Rattus norvegic...
 688.0 [0..9] [1100..26]
TBCD_MOUSE - Tubulin-specific chaperone D OS=Mus musculus GN=Tbcd PE=1 SV=1
 688.0 [0..9] [1100..26]
TBCD_BOVIN - Tubulin-specific chaperone D OS=Bos taurus GN=TBCD PE=1 SV=1
 680.0 [0..3] [1100..25]
ALP1_SCHPO - Tubulin-folding cofactor D OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=alp1 PE=1 SV=2
gi|5915683, gi|1... - gi|5915683|sp|Q10197.2|ALP1_SCHPO RecName: Full=Tubulin-folding cofactor D; AltName: Full=Altered po...
 677.0 [0..1] [1107..1]

Back

Predicted Domain #1
Region A:
Residues: [1-879] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEEESLEGI ISIDESLITS RLSQILDDVL DDRSSSHSVE KLKDVAVKYL QFCQFQPTLL  60
   61 DKLLSKYVPN LASYLLKVKN IGKCNSITVI LYQFCKIRGY KAVRVLFPVG VQYIKELYTL 120
  121 LNESSNNTWH FHYIVLLWLS QALNTPFPLN SLDDSLDVKK TIYTIAIKYL ENSGIDKEAS 180
  181 CLVLSRLFSR DDGLDLLLGF LHHCESSWFK RSIFYKIGCL FSLSSFLKIC PRNDCLQTVD 240
  241 VAFQFLNVAR EDLVGQENSA LRKLLCKCYT RLGIVLLPVN SSPNWKYSIS NPDSFFQLPD 300
  301 DSNEEVHIYL EVIVDFLLSS VSDIDSFVRW SAAKGLAKII SRLPWNLAEQ VIDAIIELMT 360
  361 ENMFLNPIEN TVNISITSPL VWHGAILFFA KLAGAGLIKY SKCLHILPLI EVGLSYEVRY 420
  421 GTRVTGQSIR DASCYFVWSF YHCYSKSAIE GLQTNLILCL LQTVLFDNEI NVRRAATAAL 480
  481 FEVIGRHASI PDGLSLISHI NYVSVTDISN CYGDLCMKVA HFPQFRSCVF QRLFTNLQHW 540
  541 DVKVQQLSAF SLRQLSIKYP KELSIYLPPI LDYLSVGNAD FIFGYTIGLA SIIGGFLSIS 600
  601 FPFDINRIHD LLSHKNLLSL KKFSRQQQTK IILGILKGIQ QIFANDIRVD RAFFSEAFSV 660
  661 IIAAIDLQEE TIIKDISDAY SVLVKFDDME ETLEVLLDYI RKCSTSKEAR IVYIILQNLP 720
  721 NISFRYQKKI CKLLLDIYPQ LHSIDYQAPV ANALQNIIPF TYEKTESIEE FVKELLQVCS 780
  781 NYLTDTRGDV GSWIRKPAMK AISSLLVKDS SGKKLSEDIV WCCISYIIRQ TFDKIDSLRG 840
  841 LAYQALEQIR VHYLIRRCEA LTNIINRISF RNNPNMDGE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 76.69897
Match: 1qbkB
Description: Karyopherin beta2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.91891696274037 bayes_pls_golite062009
cytoskeletal protein binding 2.61566088685247 bayes_pls_golite062009
actin binding 1.76244772281676 bayes_pls_golite062009
protein binding 1.75981610748679 bayes_pls_golite062009
nucleic acid binding 1.13208464017585 bayes_pls_golite062009
structural molecule activity 0.440301695287117 bayes_pls_golite062009
DNA binding 0.171056781378569 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [880-1016] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VLNELNISLL EIPNLRLQAF YGITVFTADG FGSDLAVKCF EFYLSYVYQL EDSFKKSNSR  60
   61 YGKRDLLQLY IDILSSEDEI ARFYFPIMKS FTSLLAYGCF TDFQNVKGMS KAIFIVQRRA 120
  121 LTCKSPGGLS AILELYR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.30103
Match: 1uklA
Description: Crystal structure of Importin-beta and SREBP-2 complex
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [1017-1107] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLFLSKNELL RHHALKYTAN LLLNPIEKVR YQAADTLLYA KSIGLLTFLP NELNQKLLTL  60
   61 DWFVPVSQNA TFVKQLRNII QKQIDKLIAD R

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score		 SCOP
Match		 SCOP Description
View Download 0.823 a.64.1 Saposin

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle