YRC Public Data Repository - Protein Structure Prediction

Protein:	aph1
Organism:	Schizosaccharomyces pombe
Length:	182 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for aph1.

Description	E-value	Query Range	Subject Range
gi\|21228060, gi\|... - gi\|21228060\|ref\|NP_633982.1\| Hit-like protein [Methanosarcina mazei Go1], gi\|20906495\|gb\|AAM31654.1\|...	168.0	[0..1]	[140..5]
gi\|19914624, gi\|... - gi\|20089695\|ref\|NP_615770.1\| histidine triad protein [Methanosarcina acetivorans C2A], gi\|19914624\|g...	166.0	[0..1]	[136..12]
gi\|221088498, gi... - gi\|221088498\|ref\|ZP_03558028.1\| histidine triad (HIT) protein [Geobacillus sp. Y412MC61], gi\|2207076... gi\|56379034, gi\|... - gi\|56419192\|ref\|YP_146510.1\| Hit-like protein (cell-cycle regulation histidine triad) [Geobacillus k... gi\|229330001, gi... - gi\|229499034\|ref\|ZP_04392724.1\| histidine triad (HIT) protein [Geobacillus sp. Y412MC52], gi\|2293300...	160.0	[0..4]	[136..6]
gi\|42736145, gi\|... - gi\|42780226\|ref\|NP_977473.1\| HIT family protein [Bacillus cereus ATCC 10987], gi\|42736145\|gb\|AAS4008...	158.0	[0..2]	[136..26]
gi\|228944776, gi... - gi\|228944776\|ref\|ZP_04107139.1\| Histidine triad (HIT) protein [Bacillus thuringiensis serovar monter... gi\|228932447, gi... - gi\|228932447\|ref\|ZP_04095328.1\| Histidine triad (HIT) protein [Bacillus thuringiensis serovar andalo... gi\|229090097, gi... - gi\|229090097\|ref\|ZP_04221347.1\| Histidine triad (HIT) protein [Bacillus cereus Rock3-42], gi\|2286931... gi\|228775520, gi... - gi\|228984233\|ref\|ZP_04144415.1\| Histidine triad (HIT) protein [Bacillus thuringiensis serovar tochig... gi\|228681699, gi... - gi\|229101751\|ref\|ZP_04232468.1\| Histidine triad (HIT) protein [Bacillus cereus Rock3-28], gi\|2286816... gi\|228687783, gi... - gi\|229095651\|ref\|ZP_04226632.1\| Histidine triad (HIT) protein [Bacillus cereus Rock3-29], gi\|2286877... gi\|228645500, gi... - gi\|229137843\|ref\|ZP_04266442.1\| Histidine triad (HIT) protein [Bacillus cereus BDRD-ST26], gi\|228645... gi\|229120665, gi... - gi\|229120665\|ref\|ZP_04249908.1\| Histidine triad (HIT) protein [Bacillus cereus 95/8201], gi\|22866267... gi\|206976570, gi... - gi\|206976570\|ref\|ZP_03237476.1\| HIT family protein [Bacillus cereus H3081.97], gi\|206745253\|gb\|EDZ56... gi\|217958634, gi... - gi\|217958634\|ref\|YP_002337182.1\| HIT family protein [Bacillus cereus AH187], gi\|217064817\|gb\|ACJ7906... gi\|195990943, gi... - gi\|196036469\|ref\|ZP_03103865.1\| HIT family protein [Bacillus cereus W], gi\|195990943\|gb\|EDX54915.1\| ... gi\|196037533, gi... - gi\|196037533\|ref\|ZP_03104844.1\| HIT family protein [Bacillus cereus NVH0597-99], gi\|196031775\|gb\|EDX... gi\|218537153, gi... - gi\|218902242\|ref\|YP_002450076.1\| HIT family protein [Bacillus cereus AH820], gi\|218537153\|gb\|ACK8955... gi\|222094782, gi... - gi\|222094782\|ref\|YP_002528842.1\| HIT family protein [Bacillus cereus Q1], gi\|221238840\|gb\|ACM11550.1... gi\|51977738, gi\|... - gi\|52144269\|ref\|YP_082558.1\| HIT family protein [Bacillus cereus E33L], gi\|51977738\|gb\|AAU19288.1\| H... gi\|47555726, gi\|... - gi\|47567531\|ref\|ZP_00238242.1\| HIT family protein [Bacillus cereus G9241], gi\|47555726\|gb\|EAL14066.1... gi\|225862994, gi... - gi\|225862994\|ref\|YP_002748372.1\| HIT family protein [Bacillus cereus 03BB102], gi\|225785642\|gb\|ACO25... gi\|49331618, gi\|... - gi\|49480062\|ref\|YP_035305.1\| HIT family protein [Bacillus thuringiensis serovar konkukian str. 97-27... gi\|228926192, gi... - gi\|228926192\|ref\|ZP_04089267.1\| Histidine triad (HIT) protein [Bacillus thuringiensis serovar pondic... gi\|228845925, gi... - gi\|228913733\|ref\|ZP_04077359.1\| Histidine triad (HIT) protein [Bacillus thuringiensis serovar pulsie...	158.0	[0..2]	[136..5]
gi\|74493712, gi\|... - gi\|75758808\|ref\|ZP_00738922.1\| Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) [Bacillus thuringie...	157.0	[0..2]	[136..26]
gi\|73669247, gi\|... - gi\|73669247\|ref\|YP_305262.1\| histidine triad protein [Methanosarcina barkeri str. Fusaro], gi\|723964...	157.0	[0..1]	[136..1]
gi\|228639713, gi... - gi\|229143760\|ref\|ZP_04272181.1\| Histidine triad (HIT) protein [Bacillus cereus BDRD-ST24], gi\|228639... gi\|228657038, gi... - gi\|229126458\|ref\|ZP_04255473.1\| Histidine triad (HIT) protein [Bacillus cereus BDRD-Cer4], gi\|228657... gi\|228674869, gi... - gi\|229108614\|ref\|ZP_04238226.1\| Histidine triad (HIT) protein [Bacillus cereus Rock1-15], gi\|2286748... gi\|30019204, gi\|... - gi\|30019204\|ref\|NP_830835.1\| bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) [Bacillus cereus ATCC...	157.0	[0..2]	[136..5]
gi\|89205598, gi\|... - gi\|89205598\|ref\|ZP_01184166.1\| Histidine triad (HIT) protein [Bacillus weihenstephanensis KBAB4], gi...	156.0	[0..2]	[136..5]
gi\|89084840, gi\|... - gi\|89100411\|ref\|ZP_01173274.1\| Hit family hydrolase [Bacillus sp. NRRL B-14911], gi\|89084840\|gb\|EAR6...	155.0	[0..3]	[136..2]

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Predicted Domain #1

Region A:
Residues: [1-182]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKQLYFSKF PVGSQVFYRT KLSAAFVNLK PILPGHVLVI PQRAVPRLKD LTPSELTDLF  60
   61 TSVRKVQQVI EKVFSASASN IGIQDGVDAG QTVPHVHVHI IPRKKADFSE NDLVYSELEK 120
  121 NEGNLASLYL TGNERYAGDE RPPTSMRQAI PKDEDRKPRT LEEMEKEAQW LKGYFSEEQE 180
  181 KE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	33.39794
Match:	1emsA
Description:	NIT-FHIT fusion protein, C-terminal domain; NIT-FHIT fusion protein, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.967106554167137	bayes_pls_golite062009
nucleic acid binding	0.724655038971066	bayes_pls_golite062009
catalytic activity	0.096119422680995	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: