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View Structure Prediction Details

Protein: pab-1
Organism: Caenorhabditis elegans
Length: 583 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pab-1.

Description E-value Query
Range
Subject
Range
gi|76689281 - gi|76689281|ref|XP_881384.1| PREDICTED: similar to Polyadenylate-binding protein 4 (Poly(A)-binding ...
473.0 [0..2] [583..44]

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Predicted Domain #1
Region A:
Residues: [1-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEMNVAAPAA AVAGAAAPQP ADAERAMDTM NFEALHGKPM RIMWSQRDPA MRRSGAGNIF  60
   61 IKNLDKVIDN KSIYDTFSLF GNILSCKVAI DEDGFSKGYG FVHFETEEAA QNAIQKVNGM 120
  121 LLAGKKVFVG KFQPRAQRNR ELGETAKQFT NVYVKNFGDH YNKETLEKLF AKFGNITSCE 180
  181 VMTVEGKSKG FGFVAFANPE EAETAVQALH DSTIEGTDLK LHVCRAQKKS ERHAELKKKH 240
  241 E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.30103
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 5.15097136329571 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
mRNA binding 4.05281507540116 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
2.60920363363072 bayes_pls_golite062009
transcription regulator activity 2.18211199677674 bayes_pls_golite062009
DNA binding 1.98418556946403 bayes_pls_golite062009
single-stranded RNA binding 1.46469774223879 bayes_pls_golite062009
poly-pyrimidine tract binding 1.36691748240059 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
transcription factor activity 1.07843408116687 bayes_pls_golite062009
mRNA 3'-UTR binding 0.824614388276642 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [242-346]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QHKAERMQKY QGVNLYVKNL DETVDDDGLK KQFESYGNIT SAKVMTDENG RSKGFGFVCF  60
   61 EKPEEATSAV TEMNSKMVCS KPLYVAIAQR KEDRRAQLAS QYMQR

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 5.1
Match: 2f3jA
Description: No description for 2f3jA was found.

Predicted Domain #3
Region A:
Residues: [347-517]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LASMRMHGNV PGAAMYNPTQ PGPGYYVANP MQQQRNFAGG QQMVRPGGRW GMQNQYPVQN  60
   61 QYMMAQGPGV YQNRMGRPQN QQGGPRGPPQ QYNQVAQGGV RMQGPPRTQN PGVQQQNVPR 120
  121 PPQQQQQQRP APTGPKAPPQ PYQAYQQRPQ GIVIGGQEPL TSAMLAAAAP Q

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.154902
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [518-583]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQKQLLGERI YALIEKLYPG HKDAGKITGM MLEIDNSELI MMLQDSELFR SKVDEAASVL  60
   61 VSAQKQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.0
Match: 1g9lA
Description: poly(A) binding protein
Matching Structure (courtesy of the PDB):

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