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View Structure Prediction Details

Protein: CE36021
Organism: Caenorhabditis elegans
Length: 427 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE36021.

Description E-value Query
Range
Subject
Range
gi|20071821, gi|... - gi|30089694|ref|NP_835742.1| cystathionine-beta-synthase isoform 2 [Mus musculus], gi|26346589|dbj|B...
345.0 [0..14] [426..26]

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Predicted Domain #1
Region A:
Residues: [1-427]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISDYFYLLF TISLLANSAL MVVTHQSSNG NRISDAPKDQ MTESKEWTRD AIQKMWSERN  60
   61 LMGSTPIHVI DPPGLPSVRL VFKNESASLT GSLKHRYSWS LMMWALLEGH VKNGTHVFEA 120
  121 SSGNTACSLG YMCRLLGLQF TAVVPDTIEQ VKVRRIEEQE GFVVRVPISD RLIIAEQLAK 180
  181 STGGFFMNQF KNAFHAEEFH ESGSASSKPS ANLMHELFHQ LNSTPPSIFV HPAGTGGTLS 240
  241 SIGRYAKKYG LDTEIVLADT QYSIYYDYVL NGTFSKNTGA HHWVAPGMAG IGYGAMGPAQ 300
  301 IAETTSLDPA VIDRVLKIPD LASTAAMKVA RDVGINGGTS TGVNFLAALH IGALIRAQNP 360
  361 KNQEIFTIAT ILADSGKYYE TTYFNRKWIS EKFKTHGGLP VYDCWLQVIQ DCWISGKDPL 420
  421 DIGRKMC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.69897
Match: 1jbqA
Description: Cystathionine beta-synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cysteine synthase activity 5.41656208810337 bayes_pls_golite062009
catalytic activity 2.76038225023173 bayes_pls_golite062009
lyase activity 2.54165185299539 bayes_pls_golite062009
carbon-oxygen lyase activity 1.52790731142158 bayes_pls_golite062009
tryptophan synthase activity 1.20598297230192 bayes_pls_golite062009
cystathionine beta-synthase activity 0.990559595514791 bayes_pls_golite062009
ammonia-lyase activity 0.943946746392831 bayes_pls_golite062009
threonine synthase activity 0.86525519885835 bayes_pls_golite062009
carbon-nitrogen lyase activity 0.8463142805916 bayes_pls_golite062009
L-threonine ammonia-lyase activity 0.57533596285038 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle