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View Structure Prediction Details

Protein: CE34935
Organism: Caenorhabditis elegans
Length: 372 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE34935.

Description E-value Query
Range
Subject
Range
gi|157774325 - gi|157774325|ref|XP_001665228.1| hypothetical protein CBG09957 [Caenorhabditis briggsae AF16]
gi|39590727, gi|... - gi|39590727|emb|CAE65097.1| Hypothetical protein CBG09957 [Caenorhabditis briggsae], gi|187031420|em...
167.0 [0..1] [372..1]

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Predicted Domain #1
Region A:
Residues: [1-234]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRRHRRSKV TRVVNLVKKI IAFFFSHIGL CALVVGYALL GAVIFKAVEG PHEAEIQELV  60
   61 KSAREKAVDV VWNATFRVNR LDSKQWKKTV LDEVKRFKTV CMLSIRKGYD GKEYGKQAQW 120
  121 TFTGAFLYSL TVITTIGYGN TAAKTYIGKT LTMLYAIIGI PLMLLFLTNI GDVMAKIFRF 180
  181 LYAQSIRLKF RLILWHKKRK AAKIRRANSL VSRLTRGHRV KADSSVDSFG LGAG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.522879
Match: 2a79B
Description: Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [235-372]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADVEDLLTAR VEMEQLEVRE TAAAQLESMT VPISLVVFTM LGYLGVGTTI FKVWEGWTFL  60
   61 ESFYFCFISL TTIGFGDKFP STSVSNTDEA QEKLVITSIY LLFGMALLAM CFNLAQEEVQ 120
  121 NKTRWIADKF RSKEDDDD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.522879
Match: 1lnqA
Description: Potassium channel-related protein MthK
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
potassium channel activity 6.80950139957332 bayes_pls_golite062009
voltage-gated potassium channel activity 6.78740036921969 bayes_pls_golite062009
voltage-gated cation channel activity 6.69340621375858 bayes_pls_golite062009
voltage-gated ion channel activity 6.55904318827964 bayes_pls_golite062009
voltage-gated channel activity 6.55320598344395 bayes_pls_golite062009
metal ion transmembrane transporter activity 5.06264960439093 bayes_pls_golite062009
cation transmembrane transporter activity 4.86252983188139 bayes_pls_golite062009
cation channel activity 4.85749153259346 bayes_pls_golite062009
ion transmembrane transporter activity 4.77144021609018 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 4.3961579058414 bayes_pls_golite062009
gated channel activity 4.19619757426613 bayes_pls_golite062009
inward rectifier potassium channel activity 4.13359972196575 bayes_pls_golite062009
substrate-specific channel activity 4.09858664479122 bayes_pls_golite062009
ion channel activity 3.86720832958006 bayes_pls_golite062009
passive transmembrane transporter activity 3.7587607940377 bayes_pls_golite062009
channel activity 3.7587607940377 bayes_pls_golite062009
transporter activity 2.93091397928047 bayes_pls_golite062009
transmembrane transporter activity 2.82224868778929 bayes_pls_golite062009
substrate-specific transporter activity 2.54207434157938 bayes_pls_golite062009
ligand-gated channel activity 2.26062383880472 bayes_pls_golite062009
ligand-gated ion channel activity 2.26062383880472 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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