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View Structure Prediction Details

Protein: CE34752
Organism: Caenorhabditis elegans
Length: 597 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE34752.

Description E-value Query
Range
Subject
Range
gi|73974152 - gi|73974152|ref|XP_857166.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...
235.0 [0..113] [596..1]

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Predicted Domain #1
Region A:
Residues: [1-90]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQGRGGYHHG FDGPKRYRRD DNADPTNPNP SIVVHVRNLH QKVTEADLLE ALSNFGPVAY  60
   61 ATCIPHSRMA LVEFEDIEGA KACVNFATSN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.30103
Match: 1wexA
Description: Solution structure of RRM domain in protein BAB28521
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
4.67888641618755 bayes_pls_golite062009
nucleic acid binding 3.81920018903278 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
binding 3.05116833253954 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
snRNA binding 1.76821382294389 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
transcription regulator activity 1.07788694919471 bayes_pls_golite062009
DNA binding 0.978604858165557 bayes_pls_golite062009
U1 snRNA binding 0.612226940931031 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
protein binding 0.42571879933058 bayes_pls_golite062009
transcription factor activity 0.234742017105535 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [91-306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QINVGGQGAL FNYSTSQCIE RMGFESATPN KVLVVTVLNA QYPIDADVIY QISNAQGKVL  60
   61 RVAVMHKPTV VQALVEFESM EVAKAAKHAM NGADIYSGCC TLKVEFAKPD RVRVQRQDKD 120
  121 QRDFTLPDNE SFQDTGRKTL IPAKPDDHYR RPYEDDRNHY DRHDYQAPSS YGYSSRGGGH 180
  181 SDYYGGDRGG PPHPPPSRYR DDYEDRGYAQ PAGGGP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.30103
Match: 1sjrA
Description: NMR Structure of RRM2 from Human Polypyrimidine Tract Binding Protein Isoform 1 (PTB1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
4.67888641618755 bayes_pls_golite062009
nucleic acid binding 3.81920018903278 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
binding 3.05116833253954 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
snRNA binding 1.76821382294389 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
transcription regulator activity 1.07788694919471 bayes_pls_golite062009
DNA binding 0.978604858165557 bayes_pls_golite062009
U1 snRNA binding 0.612226940931031 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
protein binding 0.42571879933058 bayes_pls_golite062009
transcription factor activity 0.234742017105535 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [307-515]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GCVMMIYGLE HGKINCDMLF NILCQYGNVL RISFMRTKTE TGIIELGTPE ERQNVLDFLQ  60
   61 GSALFGLTLE FKPSHQECVH HLRDPFLLPD GSPSFKDYSS SRNQRFSTPE LAAKNRIIFP 120
  121 TNTLHWFNAP GTMDEQALLD LMAEKTEHKP VKIDIFPSRN ERSAAGTAEF ETVEIANEVL 180
  181 ALVNHTPVNS PYGSAPFIVK WAYATPRRW

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.69897
Match: 1qm9A
Description: Polypyrimidine tract-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
4.67888641618755 bayes_pls_golite062009
nucleic acid binding 3.81920018903278 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
binding 3.05116833253954 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
snRNA binding 1.76821382294389 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
transcription regulator activity 1.07788694919471 bayes_pls_golite062009
DNA binding 0.978604858165557 bayes_pls_golite062009
U1 snRNA binding 0.612226940931031 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
protein binding 0.42571879933058 bayes_pls_golite062009
transcription factor activity 0.234742017105535 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [516-597]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGSGGEPPRY EEGGDGERKE GFIQPAHRPS PSFRGRGRGY GDSGFRRESY RGGLHGSDRY  60
   61 GPYPPRGGGF RGGRGRGRFD GY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle