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View Structure Prediction Details

Protein: tsg-101
Organism: Caenorhabditis elegans
Length: 425 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tsg-101.

Description E-value Query
Range
Subject
Range
gi|50747848 - gi|50747848|ref|XP_421014.1| PREDICTED: similar to tumor susceptibility protein 101 [Gallus gallus]
417.0 [0..2] [424..377]

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Predicted Domain #1
Region A:
Residues: [1-141]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAHQVQQCL QRAGGKYADS AKKDIIGALS QFKDLSPGTD TFMFPDGKRR TAFRLKGTIP  60
   61 VYYKGACYNI PVTVYLWDTH PYYAPICYVN PTSTMVIKES EHVNKEGKVF LPYLNEWRFP 120
  121 GYDLSGLLQV MAMVFQEKCP V

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.69897
Match: 1kppA
Description: Tumor susceptibility gene 101 (TSG101) UEV domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small conjugating protein ligase activity 0.45543793305446 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.181948894099648 bayes_pls_golite062009
protein binding 0.030781579956521 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [142-268]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FARSAANSAT NASATNPSAG SSASSTPTPY PSSQPTMPTP YPTGSGAAPY PPSSTPYPSA  60
   61 GAMGYNPYMN VPQSTPYPMG ASGASPYPSA SSNPAPPPPR PPPVTAQTSV SSSSGGTIQA 120
  121 DTIRASV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.522879
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [269-425]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAVEEKIRA KLRERMGTNS AEMASIRTTS DELREGQQKL KRMLEELETQ RSSLQTACEI  60
   61 YTAKKAELAK ALSDAGGTDA PPIDEAIDAA FPLHRQIVLN YAKDLTCDDV IYSLGQSLKK 120
  121 RQITLAEYLR HVRDVSREQF IYRATMQKCR RTAGLPI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.0
Match: 2p22A
Description: No description for 2p22A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle