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View Structure Prediction Details

Protein: zag-1
Organism: Caenorhabditis elegans
Length: 596 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for zag-1.

Description E-value Query
Range
Subject
Range
gi|76651068 - gi|76651068|ref|XP_887912.1| PREDICTED: similar to zinc finger protein 192 isoform 5 [Bos taurus]
786.0 [0..3] [594..326]

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Predicted Domain #1
Region A:
Residues: [1-128]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVDIAEAMPT TASSLPSDEA LRKFKCPECT KAFKFKHHLK EHIRIHSGEK PFECQQCHKR  60
   61 FSHSGSYSSH MSSKKCVQQA SPSMVTPFNP YQLMMYRNIM LQLQTPQVSF LPSTAANNMD 120
  121 YMSLLQAN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.045757
Match: 2dlkA
Description: No description for 2dlkA was found.

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.14649486810497 bayes_pls_golite062009
DNA binding 2.89992872665011 bayes_pls_golite062009
nucleic acid binding 2.66588130528088 bayes_pls_golite062009
transcription factor activity 1.97913234583912 bayes_pls_golite062009
binding 1.7678140110688 bayes_pls_golite062009
transcription repressor activity 1.56441586442357 bayes_pls_golite062009
protein binding 1.33682539095771 bayes_pls_golite062009
catalytic activity 0.616333600617445 bayes_pls_golite062009
transcription activator activity 0.35578487491271 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.29294316958168 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [129-196]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LFQSLENGTS PTPTQEPSAP ASPEPKIEVV DEPEVSSEVK TEVKTEVKTE DSVPEESITP  60
   61 AVSMSLSP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [197-349]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APEQNGNESM NNGGSGSDGK SSPDWRPLRS RSFLNDSQVA VLQNHFKRNP FPSKYELSAV  60
   61 AEQIGVNKRV VQVWFQNTRA KERRSNRLPS MPRGSVASAA AAAATSPTVW QTPVQLMAAW 120
  121 ASQFSNGNNS LTASQDERNN ENTDEVMDHD GLK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.69897
Match: 1tf6A
Description: Transcription factor IIIA, TFIIIA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.14649486810497 bayes_pls_golite062009
DNA binding 2.89992872665011 bayes_pls_golite062009
nucleic acid binding 2.66588130528088 bayes_pls_golite062009
transcription factor activity 1.97913234583912 bayes_pls_golite062009
binding 1.7678140110688 bayes_pls_golite062009
transcription repressor activity 1.56441586442357 bayes_pls_golite062009
protein binding 1.33682539095771 bayes_pls_golite062009
catalytic activity 0.616333600617445 bayes_pls_golite062009
transcription activator activity 0.35578487491271 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.29294316958168 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [350-430]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGKETPLDLT LSTDDTEPEW SPEKLIGFLD QTGGVIQELL RQAGNGFVTN QEDEEEKPIK  60
   61 AEESPVSSGS SSIWPSFIGQ Y

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.983
Match: 1neqA
Description: SOLUTION STRUCTURE OF THE MU NER PROTEIN BY MULTIDIMENSIONAL NMR
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA binding 3.50333148278009 bayes_pls_golite062009
transcription regulator activity 3.22435490927648 bayes_pls_golite062009
nucleic acid binding 3.13941403740118 bayes_pls_golite062009
binding 2.1596228032617 bayes_pls_golite062009
transcription factor activity 2.10376028888832 bayes_pls_golite062009
transcription repressor activity 1.47303242361831 bayes_pls_golite062009
protein binding 0.835527357717776 bayes_pls_golite062009
catalytic activity 0.416161499675821 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.0407275201491086 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [431-596]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSILDSASLS VLEKALDQQK SSEDDASSLC SNESKLLKFP TTPLKEEEGL FSCDQCDKVF  60
   61 GKQSSLARHK YEHSGQRPYK CDICEKAFKH KHHLTEHKRL HSGEKPFQCD KCLKRFSHSG 120
  121 SYSQHMNHRY SYCKPYREQP ASPSDVLNGG SVTVSPSSSN TPPPST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 57.154902
Match: 2i13A
Description: No description for 2i13A was found.

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