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View Structure Prediction Details

Protein: CE33940
Organism: Caenorhabditis elegans
Length: 462 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE33940.

Description E-value Query
Range
Subject
Range
gi|166853413, gi... - gi|167039173|ref|YP_001662158.1| response regulator receiver protein [Thermoanaerobacter sp. X514], ...
gi|167038115, gi... - gi|76796702|ref|ZP_00779057.1| IMP dehydrogenase [Thermoanaerobacter ethanolicus ATCC 33223], gi|765...
gi|241902681, gi... - gi|241902681|ref|ZP_04787413.1| inosine-5'-monophosphate dehydrogenase [Thermoanaerobacter brockii s...
375.0 [0..24] [461..2]

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Predicted Domain #1
Region A:
Residues: [1-462]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVRPEDFNSL ELDNSLTDGE TVHEMMAHKA GLTYNDFNIL PGFINFGVHD VSLETNITKD  60
   61 LKIKAPLVSS PMDTVTESGM AIVMALYGGI GIIHGNFPKP EDQAAEVLKV KRFKQGYVMQ 120
  121 PHCLSRDSTA FDMIQIKKKY GYTGAPVTED GRVGSKLIGM VTSRDFDFIT MDVAGQKGTP 180
  181 ISDTNDVTPT TPITRIMVSV DQLHLGHIND APELSQKKLK EHRLGKLPIV NDNGELCALL 240
  241 CRSDLLKARD YPMASYDSKG QLLCGAAVNT RGESQYTVDR VVEAGVDVLI IDSSNGSSTY 300
  301 QISMLRYIKE KHPHVQVIAG NVVTRAQAKL LIDQGADGLR IGMGSGSICI TQDVMAVGRA 360
  361 QGTAVYDVAR YANQRGIPIV ADGGIRDVGY ITKAISLGAS AVMMGGLLAA TTEAPGEYFW 420
  421 GPGGVRVKKY RGMGSLDAME AHASSQDRYF TAHVFFSILS YF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 96.0
Match: 1b3oA
Description: Inosine monophosphate dehydrogenase (IMPDH)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
substrate-specific transporter activity 2.7174579941626 bayes_pls_golite062009
ion transmembrane transporter activity 2.67550158046797 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.37454569900522 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 2.25981040434391 bayes_pls_golite062009
cation transmembrane transporter activity 2.02076988939348 bayes_pls_golite062009
IMP dehydrogenase activity 2.02048863053452 bayes_pls_golite062009
binding 0.964202692685807 bayes_pls_golite062009
protein binding 0.22179604283012 bayes_pls_golite062009
catalytic activity 0.181756622780318 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle