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View Structure Prediction Details

Protein: pyp-1
Organism: Caenorhabditis elegans
Length: 406 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pyp-1.

Description E-value Query
Range
Subject
Range
pyp-1 - inorganic pyrophosphatase status:Confirmed UniProt:Q18680 protein_id:CAD89726.1
478.0 [0..1] [406..1]

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Predicted Domain #1
Region A:
Residues: [1-117]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGCAVSQESA IATVSSSSNT ATTSTSSSNT SQKWATSRTS RPVTNVTQVS AIHTTSMDSG  60
   61 SSTVQLPSPR GSLTTAVSTS SSGAQRQMSA NSERSLHTRP LSETAVILQS QAVKMST

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [118-406]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAGDSAVYEA VERGSLYSLD YRVYIKGPQG IVSPWHDIPL FANKDKRVYN MIVEIPRWTN  60
   61 AKMEMATKEP FSPIKQDEKK GVARFVHNIF PHKGYIWNYG ALPQTWEDPN HVVPDTGAKG 120
  121 DNDPIDVIEV GSKVAGRGAV LQVKVLGTLA LIDEGETDWK LVAIDVNDEN ADKLNDIDDV 180
  181 EKVYPGLLAA SVEWFRNYKI PAGKPANEFA FNGEFKNREY AEKVIDETNE YWKTLIKEAN 240
  241 PSLNTVSRVP EAVHQGTDEA AATAIGATPE HGANAPLPGD VDKWHFVQG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 103.0
Match: 1m38A
Description: Inorganic pyrophosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
inorganic diphosphatase activity 2.74116819406619 bayes_pls_golite062009
binding 1.77492613217844 bayes_pls_golite062009
catalytic activity 1.33262120571864 bayes_pls_golite062009
protein binding 0.38607803003281 bayes_pls_golite062009
pyrophosphatase activity 0.354425639853757 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.334860448536013 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.333575715544697 bayes_pls_golite062009
hydrolase activity 0.0110854177718558 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle