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View Structure Prediction Details

Protein: ref-2
Organism: Caenorhabditis elegans
Length: 302 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ref-2.

Description E-value Query
Range
Subject
Range
gi|73947291 - gi|73947291|ref|XP_541354.2| PREDICTED: similar to Zinc finger protein 606 (Zinc finger protein 328)...
502.0 [0..3] [301..2533]

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Predicted Domain #1
Region A:
Residues: [1-87]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHSDYYTQSQ GPTVEQQPEW QASVQPYSDP HAYSPSFYMN MSQVPHFLPA QVDPFIYPNT  60
   61 LGSYGGDKQV QCLWETNGQV CMHVCQN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.69897
Match: 1bboA
Description: HIGH-RESOLUTION SOLUTION STRUCTURE OF THE DOUBLE CYS2*HIS2 ZINC FINGER FROM THE HUMAN ENHANCER BINDING PROTEIN MBP-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.61993443866178 bayes_pls_golite062009
DNA binding 0.94762880941053 bayes_pls_golite062009
transcription regulator activity 0.83697324179524 bayes_pls_golite062009
nucleic acid binding 0.393163105327437 bayes_pls_golite062009
protein binding 0.309302474986083 bayes_pls_golite062009
transcription factor activity 0.21812283292306 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [88-123]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGELSTHISS NHITHDSKFV CLWKGCDREF KMFKAK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.522879
Match: 2gliA
Description: Five-finger GLI1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [124-302]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YKLVNHMRVH TGERPFLCDV CNKVFARSEN LKIHKRIHSG EKPFQCTHNG CTKLFANSSD  60
   61 RKKHMHVHSS HKPYSCMYPD CGKTYTHPSS LRKHTKVHEN EKKSQLSPEH DESSDSGNAS 120
  121 IGTPTTDESL TFSPENIKRD QHLHTMHTFM DRPNPFMQMY QNQFSNPTYH MFMAKPDSY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 57.522879
Match: 2i13A
Description: No description for 2i13A was found.

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