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View Structure Prediction Details

Protein: klc-2
Organism: Caenorhabditis elegans
Length: 501 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for klc-2.

Description E-value Query
Range
Subject
Range
gi|113476999, gi... - gi|113476999|ref|YP_723060.1| peptidase-like [Trichodesmium erythraeum IMS101], gi|110168047|gb|ABG5...
357.0 [0..6] [500..177]

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Predicted Domain #1
Region A:
Residues: [1-116]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNMSQDDVT TGLRTVQQGL EALREEHSTI SNTLETSVKG VKEDEAPLPK QKLSQINDNL  60
   61 DKLVCGVDET SLMLMVFQLT QGMDAQHQKY QAQRRRLCQE NAWLRDELSS TQIKLQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.39794
Match: 1xi4A
Description: Clathrin D6 Coat
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [117-501]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSEQMVAQLE EENKHLKYMA SIKQFDDGTQ SDTKTSVDVG PQPVTNETLQ ELGFGPEDEE  60
   61 DMNASQFNQP TPANQMAASA NVGYEIPARL RTLHNLVIQY ASQGRYEVAV PLCKQALEDL 120
  121 EKTSGHDHPD VATMLNILAL VYRDQNKYKE AANLLNEALS IREKCLGESH PAVAATLNNL 180
  181 AVLFGKRGKF KDAEPLCKRA LEIREKVLGD DHPDVAKQLN NLALLCQNQG KYEEVEKYYK 240
  241 RALEIYESKL GPDDPNVAKT KNNLSSAYLK QGKYKEAEEL YKQILTRAHE REFGQISGEN 300
  301 KPIWQIAEER EENKHKGEGA TANEQAGWAK AAKVDSPTVT TTLKNLGALY RRQGKYEAAE 360
  361 TLEDVALRAK KQMSESRRME RSVMY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.045757
Match: 1w3bA
Description: The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.14253214573541 bayes_pls_golite062009
protein binding 1.65083457326273 bayes_pls_golite062009
signal sequence binding 0.49295886046194 bayes_pls_golite062009
peroxisome targeting sequence binding 0.0468412220974996 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle