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View Structure Prediction Details

Protein: frm-8
Organism: Caenorhabditis elegans
Length: 784 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for frm-8.

Description E-value Query
Range
Subject
Range
frm-8 - status:Partially_confirmed UniProt:Q8MXE9 protein_id:AAM48544.1
505.0 [0..1] [784..1]

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Predicted Domain #1
Region A:
Residues: [1-86]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKSKSLQFH AGGSQSPPKR ICCSGSVDEI KDLIHTTRSS HWEPPWASWR CRLGLPYGWE  60
   61 QAKDNDGNTY YIDHLNRTTT YTDPRK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.39794
Match: 1tk7A
Description: NMR structure of WW domains (WW3-4) from Suppressor of Deltex
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [87-194]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TRPPDGKRTV SIRRGKDIGF GFVAAGQLPT IIQFVSPEGP SDGLLYANDQ ILEVNGLDMQ  60
   61 NETKDNVVNA VRAAKEELQI TVQQLPQRPK SSRKNCKVRF TDRVLVSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.69897
Match: 2csjA
Description: Solution structure of N-terminal PDZ domain from mouse TJP2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.566291652083235 bayes_pls_golite062009
protein binding 0.52823753548825 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [195-784]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNDNNSEFPP LLPNVLRVYL ENGQTRSFKY DQSTTVKQIL ESILEKLQIS AKSHFSLAVE  60
   61 YSLGARTSRI SLLRPDCKIK SIVDLPNSEH LRCVFRLSFA PSDAFVLLLS DPKALEYYYQ 120
  121 QCVNDVVRGR FAMEMRYEAC IRLAALHVQQ VAYDCNILKE NNKVSVHRVE KEYGLGTFLP 180
  181 AIVLENVKRR DVRKHIRFYL KRDSSRLVDC FGKPTIGNGY PPELEACAAQ FANEPSMMVR 240
  241 LRYIHIVSHL PSFGGRSFCV TFKESQIDML MQVEPRTGLL VRHPGKSGQP SISIGFDLIG 300
  301 KLVVCKETEV ASMISIRLAS NPHQGLEFLV DKDDLDDLVM YIVGYHKVTY EKDLLLEIDD 360
  361 SPPKLRELPD KAPPYSAIHT VVKSDWNYSE TSSQTEKPFD PTDGPPSYEI ANSFVQIAFE 420
  421 NEQNEDHFDT EISRQNGESF TPKRAHFEPK KLLRATDSLL IKNSRDLHAK ELEIQNGGSQ 480
  481 NDESSDTEDS SFSSPLRSPN IDRLCDGINL LVTGPPARRA SIETLLQNNQ NPNTNLESLI 540
  541 LQFPTIPDEN EVENDDVALP EGMQTSTTTV VANGKTRCYR NGSCAKSYQG 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.0
Match: 2i1jA
Description: No description for 2i1jA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle