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View Structure Prediction Details

Protein: CE32212
Organism: Caenorhabditis elegans
Length: 418 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE32212.

Description E-value Query
Range
Subject
Range
gi|15418718 - gi|15418718|gb|AAG23293.1| inositol polyphosphate 5-phosphatase II isoform [Mus musculus]
321.0 [0..10] [418..253]

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Predicted Domain #1
Region A:
Residues: [1-70]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDANTPSASG GDPKSGDSSS EKQSHQTPTR HPPWLRSSSQ PATWRNSASF NEISDGNWTY  60
   61 CIETQNTAPA 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [71-418]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VKGFGNVPIV SYDVIEAMGD RKLKVCTVTW NINEKGVKIL SHLAQKIAER GQEMDSDIFF  60
   61 ISLQEIPSTA PTFHEEALRI LEPVLNGHRL YLSHRAWSQM VIVFIRQKHL RYAIQPQVSF 120
  121 IASGAMAKPV RTKGAIAVCL RLYQRFIVLI GCHLSHATPQ QRIQDYAKVV RTLRFPQLAR 180
  181 FHAHAKDEIF GSDVVLWIGD LNFRVTVESN VDWRDPEKIT EKTFRDVFET EELASHRKKQ 240
  241 LAFTDFKEAP IKFPPTHKFE PDTDNYVPKR IPSFTDRVLF WVRNSEWLQN IQYDCMRGTT 300
  301 PSDHKAVFAT FWLTVINKPV PEHYKQQKSL EREISMKTNS VDASGPVN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.0
Match: 1i9yA
Description: Synaptojanin, IPP5C domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity, acting on ester bonds 5.72214109138278 bayes_pls_golite062009
phosphatase activity 5.17657305075351 bayes_pls_golite062009
phosphoric ester hydrolase activity 5.15160939023802 bayes_pls_golite062009
hydrolase activity 4.35205866750604 bayes_pls_golite062009
inositol or phosphatidylinositol phosphatase activity 3.27823550449795 bayes_pls_golite062009
catalytic activity 2.13555370693179 bayes_pls_golite062009
inositol trisphosphate phosphatase activity 2.06144653446228 bayes_pls_golite062009
phosphatidylinositol bisphosphate phosphatase activity 1.82782913783123 bayes_pls_golite062009
phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1.69849759149857 bayes_pls_golite062009
phosphoinositide 5-phosphatase activity 1.69849759149857 bayes_pls_golite062009
inositol-polyphosphate 5-phosphatase activity 1.47975493654719 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle