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View Structure Prediction Details

Protein: CE31670
Organism: Caenorhabditis elegans
Length: 704 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE31670.

Description E-value Query
Range
Subject
Range
gi|157767906 - gi|157767906|ref|XP_001675774.1| Hypothetical protein CBG01937 [Caenorhabditis briggsae AF16]
gi|39590967, gi|... - gi|39590967|emb|CAE58747.1| Hypothetical protein CBG01937 [Caenorhabditis briggsae], gi|187037694|em...
570.0 [0..1] [704..1]

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Predicted Domain #1
Region A:
Residues: [1-322]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIQNEVSATH GSTKKGITYN TILEAAQRPT PLVPLKKLKV EHQLQSDIYV KLEYLNIAGS  60
   61 LEDRTADKAF QFAEEIGVVR GDEVFVTAGG SAAISYATVA AVKGIKLTIY APKGEFDLVD 120
  121 TVLHTLGVKT VELPFGTFAE ARVQTDEAAQ QKGVFSLNKF TTNAAFVANL QKTALEIEKA 180
  181 VNNKSIGKVG AVVIPLNTGA AAAGIAAYYK GIGEHGVRVV GVTCKKDTIP EMGLDLKNDL 240
  241 LQEYNVEKRE VEEDEAYSFT RHLIGTEGIM AGPSSGAAVL EAIKLAKELP AGSTIVVVLM 300
  301 DGIRNYLRHF LDDDWITANK KD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.522879
Match: 1wdwB
Description: Structural basis of mutual activation of the tryptophan synthase a2b2 complex from a hyperthermophile, Pyrococcus furiosus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cysteine synthase activity 5.18562032111987 bayes_pls_golite062009
catalytic activity 2.38994231321972 bayes_pls_golite062009
lyase activity 1.87743897464083 bayes_pls_golite062009
cystathionine beta-synthase activity 1.4517088142802 bayes_pls_golite062009
tryptophan synthase activity 1.04832999357666 bayes_pls_golite062009
carbon-oxygen lyase activity 0.923824749425553 bayes_pls_golite062009
threonine synthase activity 0.727838845253199 bayes_pls_golite062009
ammonia-lyase activity 0.476674617721478 bayes_pls_golite062009
L-threonine ammonia-lyase activity 0.37325071016009 bayes_pls_golite062009
carbon-nitrogen lyase activity 0.249761226675912 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [323-704]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VVTRKDGPQP NSIYDPKVLV YDPTKLAGEW TQDPETKSWS HSEVEFNKFN PERPLVLDTV  60
   61 LDAIGKTPLV KLQHIPKAHG VKCNVYVKCE YMNAGGSTKD RIAKRMVEIA EKTGKPGKLV 120
  121 PGVTLIEPTS GNTGIGLSLA SAVRGYKCII TMPKKMSKEK SIAMASLGST IIRTPNEAGF 180
  181 DSPHSHIGVA LRLKSEIQDA VVLDQYCNPG NPLAHYEETA EEIIYDMGDK HIDLVVLTAG 240
  241 TGGTVTGISR KIHERIPTAK VVGVDPHGSI LAGPAETDID FYEVEGIGYD FLPGTLDTSA 300
  301 IDYWAKSHDK ESFLMARELI RSEGILCGGS SGCAVHYALE ECKSLNLPAE ANVVVLLPDG 360
  361 IRNYITKFLD DDWMNERHFL DA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 107.0
Match: 1m54A
Description: Cystathionine beta-synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cysteine synthase activity 5.18562032111987 bayes_pls_golite062009
catalytic activity 2.38994231321972 bayes_pls_golite062009
lyase activity 1.87743897464083 bayes_pls_golite062009
cystathionine beta-synthase activity 1.4517088142802 bayes_pls_golite062009
tryptophan synthase activity 1.04832999357666 bayes_pls_golite062009
carbon-oxygen lyase activity 0.923824749425553 bayes_pls_golite062009
threonine synthase activity 0.727838845253199 bayes_pls_golite062009
ammonia-lyase activity 0.476674617721478 bayes_pls_golite062009
L-threonine ammonia-lyase activity 0.37325071016009 bayes_pls_golite062009
carbon-nitrogen lyase activity 0.249761226675912 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle