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View Structure Prediction Details

Protein: ife-1
Organism: Caenorhabditis elegans
Length: 212 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ife-1.

Description E-value Query
Range
Subject
Range
gi|50746789 - gi|50746789|ref|XP_420655.1| PREDICTED: similar to eIF-4E [Gallus gallus]
269.0 [0..2] [199..72]

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Predicted Domain #1
Region A:
Residues: [1-212]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTETEQTTAP IYPLKRNWTW WYLNDERNKS WEDRLKKVYT FNTVSEFWAL YDAIRPPSGL  60
   61 NALCDYNVFR DDIQPMWEVP ENSNGGRWLI VIDKGKTPEM VDAIWLEILM ALVGEQFGKD 120
  121 MESICGLVCN VRGKGSKISV WTKDCNDDET NMRIGVVLKE KLMAASKDHS KPLFDVIRYE 180
  181 DHESCQKKTS SVVKAKLSLH SSDAPVAEKS AV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.221849
Match: 1ej1A
Description: Translation initiation factor eIF4e
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
translation initiation factor activity 12.6022960879923 bayes_pls_golite062009
RNA cap binding 8.70938037002519 bayes_pls_golite062009
translation factor activity, nucleic acid binding 7.91586572659635 bayes_pls_golite062009
translation regulator activity 7.87578736455963 bayes_pls_golite062009
RNA binding 4.73187299490341 bayes_pls_golite062009
nucleic acid binding 3.46353214508261 bayes_pls_golite062009
binding 2.88787215275737 bayes_pls_golite062009
protein binding 0.873044754151905 bayes_pls_golite062009
RNA 7-methylguanosine cap binding 0.544036568660606 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle