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View Structure Prediction Details

Protein: cah-2
Organism: Caenorhabditis elegans
Length: 337 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cah-2.

Description E-value Query
Range
Subject
Range
gi|73762630 - gi|73762630|gb|AAZ83742.1| carbonic anhydrase [Petromyzon marinus]
291.0 [0..5] [275..2]

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Predicted Domain #1
Region A:
Residues: [1-274]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIPWLLTACI YPCVIGPDFW GLLHGDWRMC TAGQMQSPVN IDPSQLLYDP HLMPINIEGN  60
   61 IVEAVFENTG QLPVVTVKDL PNRPTINITG GPTMPYRYKL HQISVHFGRA DEGEKGSEHT 120
  121 VDRVRFPAEI QLLAYNSALY PNFSVAMTSP RGLLAVSVIV DIGKTTSVEL RRLTVASQSI 180
  181 NYKGQTTNLT DFQPSALLPK TSHYVTYEGS LTFPGCHETV TWVILNNPIY ITNDDLQIWN 240
  241 EMQKTETKQP EPSYMTPAYR PLKSLNGRLV RTNI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 75.221849
Match: 1ugfA
Description: HUMAN CARBONIC ANHYDRASE II [HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY THR (A65T)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.59667704693142 bayes_pls_golite062009
protein binding 1.30419076438266 bayes_pls_golite062009
catalytic activity 0.97285738666961 bayes_pls_golite062009
transition metal ion binding 0.36067052386032 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [275-337]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVGSKQSTVS SSCPSNVYVE MGYQANPGRN KRNDSVSRRY VPTSEVFEID SIRPDDVSKA  60
   61 GSF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle