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View Structure Prediction Details

Protein: gro-1
Organism: Caenorhabditis elegans
Length: 430 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gro-1.

Description E-value Query
Range
Subject
Range
gi|109477172, gi... - gi|62649589|ref|XP_342906.2| PREDICTED: similar to tRNA isopentenyltransferase 1 [Rattus norvegicus]...
392.0 [0..15] [426..20]

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Predicted Domain #1
Region A:
Residues: [1-360]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIFRKFLNFL KPYKMRTDPI IFVIGCTGTG KSDLGVAIAK KYGGEVISVD SMQFYKGLDI  60
   61 ATNKITEEES EGIQHHMMSF LNPSESSSYN VHSFREVTLD LIKKIRARSK IPVIVGGTTY 120
  121 YAESVLYENN LIETNTSDDV DSKSRTSSES SSEDTEEGIS NQELWDELKK IDEKSALLLH 180
  181 PNNRYRVQRA LQIFRETGIR KSELVEKQKS DETVDLGGRL RFDNSLVIFM DATPEVLEER 240
  241 LDGRVDKMIK LGLKNELIEF YNEHAEYINH SKYGVMQCIG LKEFVPWLNL DPSERDTLNG 300
  301 DKLFKQGCDD VKLHTRQYAR RQRRWYRSRL LKRSDGDRKM ASTKMLDTSD KYRIISDGMD 360
  361 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 93.0
Match: 2qgnA
Description: No description for 2qgnA was found.

Predicted Domain #2
Region A:
Residues: [361-430]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVDQWMNGID LFEDISTDTN PILKGSDANI LLNCEICNIS MTGKDNWQKH IDGKKHKHHA  60
   61 KQKKLAETRT 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.71
Match: 1zr9A
Description: Solution Structure of a Human C2H2-type Zinc Finger Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 2.37910043444615 bayes_pls_golite062009
DNA binding 2.34410707831983 bayes_pls_golite062009
transcription regulator activity 2.33505949768575 bayes_pls_golite062009
binding 2.15905417087312 bayes_pls_golite062009
transcription factor activity 1.47482918271021 bayes_pls_golite062009
protein binding 0.852654490075478 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.642848769534094 bayes_pls_golite062009
RNA binding 0.332063226840189 bayes_pls_golite062009
transcription activator activity 0.294719498389745 bayes_pls_golite062009
catalytic activity 0.263007611601737 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle