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View Structure Prediction Details

Protein: hrpf-2
Organism: Caenorhabditis elegans
Length: 610 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hrpf-2.

Description E-value Query
Range
Subject
Range
gi|76689289 - gi|76689289|ref|XP_881630.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
274.0 [0..65] [588..12]

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Predicted Domain #1
Region A:
Residues: [1-242]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEQTTQPTT EDQQSAEIAV KEEEIAVKTQ SAPADAPDIH QSTIKEADES MPTKISSGEP  60
   61 PRSQYIRLRG LPFNATEKDI HEFFAGLTIE RVKFVCTTGR PNGEAYVEFK NTEEAGKAME 120
  121 NDRKEISNRY IEVFTVEADE AEFEFRPDPD SNGEVNHVIR LRGVPWSCKE DDVRKFFEGL 180
  181 EPPPAEIVIG GTGGPRSRPS GEAFVRFTTQ DAAEKAMDYN NRHMGSRYVE VFMSSMVEFN 240
  241 RA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.39794
Match: 1pgzA
Description: Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.10590295737522 bayes_pls_golite062009
nucleic acid binding 1.43479844212501 bayes_pls_golite062009
RNA binding 0.426544317458995 bayes_pls_golite062009
protein binding 0.303849616374798 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [243-417]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGGGSGEYSA SYERTGIRPL MSVDSGYDHG RRGGGGRYGD SSYDRGYDDY NRGSYGGRRD  60
   61 YGYNGGHDQG GRSDYGRGGD DPLRVYMRGL PYDADDHAIA AFFSPLRCHS VKIGINETGR 120
  121 PSGDAIAEFD NYNDLQVALS RNNQRMGRRY VELFDNRGAP GPMRRLLWKE TSGTN

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.98
Match: 1l3kA
Description: Nuclear ribonucleoprotein A1 (RNP A1, UP1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.94223327190566 bayes_pls_golite062009
nucleic acid binding 1.16612452230529 bayes_pls_golite062009
protein binding 0.239750622810233 bayes_pls_golite062009
RNA binding 0.0177644575880578 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [418-610]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASAAPAPDPI LNGGRRGGGP PQRDSGYRAG PQAMPPSYRE SRDPYGPREP RGYDIEPKYE  60
   61 PRGIPPRSAP IRAPPAAHGR APDTWGSYGA ASTGPSYDQS SAAGGYAASW DAYYASQAQS 120
  121 AYSAEPASTY PTAAHSAYGS GESYSYGASA GGAYDRQREP RDSQPTWAQQ QQPSHHSAYG 180
  181 GWGAGAGDHR SGY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.69897
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
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