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View Structure Prediction Details

Protein: smg-4
Organism: Caenorhabditis elegans
Length: 368 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for smg-4.

Description E-value Query
Range
Subject
Range
gi|7549210 - gi|7549210|gb|AAF63787.1|AF142406_1 200 kDa antigen p200 [Babesia bigemina]
143.0 [0..44] [364..200]

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Predicted Domain #1
Region A:
Residues: [1-84]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDSKDGHVK VVLRRLPKYM TEHEVLEQIS PLPEEVIGTY FHPANFSFDR CAYATLTVNF  60
   61 SEYCDSMMEF ERRFDGYIFV DSRG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.09691
Match: 1uw4A
Description: The structural basis of the interaction between nonsense mediated decay factors UPF2 and UPF3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 3.75748736237159 bayes_pls_golite062009
mRNA binding 2.67679675039933 bayes_pls_golite062009
nucleic acid binding 2.39584426231036 bayes_pls_golite062009
binding 1.71154446874967 bayes_pls_golite062009
single-stranded RNA binding 0.61170301639809 bayes_pls_golite062009
protein binding 0.426607329742248 bayes_pls_golite062009
0.24850555804347 bayes_pls_golite062009
hydrolase activity 0.0430264134452161 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [85-368]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDSAAVVEAA SNQNFAKCDR NRMKEDTRVG AILTDKYYLD FCKKLEEERA IPILTLEQQI  60
   61 RKLNQPDDAR TQIDKMETPL VKYFFEKETG KRRDYDARRQ RRDEKRAEKR DKVDKFEKHK 120
  121 NVLDILMKPS VPMASTSATT SKKDLKKEKP MTEKEKERWE KQDAKRKERN MIRKQKFLDE 180
  181 KKKKHEEREQ DGPRVPRDKK KERLAKPPRP SPAKTVGEQQ GEDWIKKLTD PKSAPMKKKH 240
  241 DLSVTTKLNK ETDTRPRTAP SSTKLPTRAT TSNHPKRPST APNH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.69897
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle