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View Structure Prediction Details

Protein: asm-1
Organism: Caenorhabditis elegans
Length: 564 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for asm-1.

Description E-value Query
Range
Subject
Range
gi|7494788 - gi|7494788|pir||T15291 sphingomyelin phosphodiesterase (EC 3.1.4.12), acidic, B0252.2 precursor [sim...
405.0 [0..1] [564..42]

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Predicted Domain #1
Region A:
Residues: [1-102]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRIIYLISTV LLIYTNATVL RTKESIQNKV TYDKYGFQPL CISCTGLISV ASFFLKFDVS  60
   61 EPVILEFATI VCKLFAKQPW AVCDGISSQF RDEFFYVFRR LA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.522879
Match: 1m12A
Description: Saposin C
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.50771902135158 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [103-564]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NESPSQICGI ILPDCADPTD PSESGWMVAL PPKPKRTRIS KKKVQKKPNM SMSQNLNVLQ  60
   61 LTDLHVDFEY KYPSEANCDD PVCCRVSVSE PKKAAGYWGS VGKCDIPFWT VENMLSHINK 120
  121 THMIDMVIMT GDYINHVDWE YSIEEHLSVL RKLHRLVQNT FPSTPIYWAL GNHEGVPVNS 180
  181 FAPHSVDERF WPTWLYKEFQ TMSGPWLSEG AKDSLLKRGS YSTQVMDGLK LITLNTGFCE 240
  241 VTNFFLYLNQ SDPDSSMSWF VKELFESEKK GEQVYVLAHI PPGDSECLEG WAFNYYRVIQ 300
  301 RFSSTIAAQF FGHDHLDYFT VFYEDMHNVS SKPISVGYAS PSVTTFEYQN PAYRIYEIDP 360
  361 YNKFKIVDFT TYYADLEKAT EDKKPVWEKL YSARQAHGMD DLSPLSWNKV IQKLFTSEKK 420
  421 REKFYQYAFR NFSPQCDSTC QMQLMCNLRM GHHNSTLYCP TF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.69897
Match: 1kbpA
Description: Purple acid phosphatase, N-terminal domain; Plant purple acid phosphatase, catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphoric ester hydrolase activity 3.1640402146807 bayes_pls_golite062009
hydrolase activity 2.06280293513737 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.62419884857008 bayes_pls_golite062009
signal transducer activity 1.5323377955218 bayes_pls_golite062009
molecular transducer activity 1.5323377955218 bayes_pls_golite062009
catalytic activity 1.39852585255405 bayes_pls_golite062009
protein binding 1.33435965029646 bayes_pls_golite062009
binding 1.01605260539008 bayes_pls_golite062009
phosphatase activity 0.887417749186372 bayes_pls_golite062009
phosphoprotein phosphatase activity 0.744264552706022 bayes_pls_golite062009
protein serine/threonine phosphatase activity 0.707342350941796 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle