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View Structure Prediction Details

Protein: yrs-1
Organism: Caenorhabditis elegans
Length: 447 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for yrs-1.

Description E-value Query
Range
Subject
Range
SYY_BACCA - Tyrosine--tRNA ligase OS=Bacillus caldotenax GN=tyrS PE=3 SV=1
408.0 [0..24] [446..1]

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Predicted Domain #1
Region A:
Residues: [1-447]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFNSKRIGNV ALKTVRAPRE SSFVDYITDL NARKQLQHSY PTDLLSKCSE DLRQLPPYVY  60
   61 AGFDPTAESL HIGNLLILVN LIRAQQFGIR PIALIGEFTA SIGDPSGKKS ERGLLAGDVI 120
  121 MHNSRKVTDQ ICKIFENAPG SSEKPIIVNN NDWLGKISLR DFLRECKNMQ VGKMLRMNTI 180
  181 KNRLEVGLSY TEFSYQTMQA FDWYTLSEKY GCRFQLGGYD QLGHLDFGAH YIKKMMNQAF 240
  241 AAGVCFPILT DSTGAKLGKS EGGGALWLDA TKTSPFHFYQ FFAQLHDDKA EELLLLFSLQ 300
  301 DIEHIRDVLK NHRSNLGQWI AQRELAAEIT RIVHGKEGLE VAMRCTKAMF GAKKADLSGL 360
  361 SRSEVLQLFR TTIDLKKENV ATMGQLADAS RLGSGKGHLL MQQGAFSVNG EKKRSPSESI 420
  421 ADVFLENASD LTLVCWGKRG YQLVRWV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 114.0
Match: 2ts1A
Description: STRUCTURE OF TYROSYL-T/RNA SYNTHETASE REFINED AT 2.3 ANGSTROMS RESOLUTION. INTERACTION OF THE ENZYME WITH THE TYROSYL ADENYLATE INTERMEDIATE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming carbon-oxygen bonds 7.16276509815667 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 7.16276509815667 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 7.13957775963187 bayes_pls_golite062009
tyrosine-tRNA ligase activity 6.18775771640881 bayes_pls_golite062009
ligase activity 6.11211476973434 bayes_pls_golite062009
glutamate-tRNA ligase activity 2.63681738794687 bayes_pls_golite062009
methionine-tRNA ligase activity 2.56893064485672 bayes_pls_golite062009
catalytic activity 2.37674226834122 bayes_pls_golite062009
arginine-tRNA ligase activity 1.50161401062914 bayes_pls_golite062009
tryptophan-tRNA ligase activity 1.14187887833901 bayes_pls_golite062009
cysteine-tRNA ligase activity 0.844943947059557 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.625793556381714 bayes_pls_golite062009
binding 0.485102284225571 bayes_pls_golite062009
nucleic acid binding 0.449504767632354 bayes_pls_golite062009
nucleotidyltransferase activity 0.2293846471193 bayes_pls_golite062009
glutamine-tRNA ligase activity 0.118292082006187 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle