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View Structure Prediction Details

Protein: CE29189
Organism: Caenorhabditis elegans
Length: 413 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE29189.

Description E-value Query
Range
Subject
Range
PCID2 - PCI domain containing 2
gi|55640145 - gi|55640145|ref|XP_509757.1| PREDICTED: hypothetical protein isoform 5 [Pan troglodytes]
318.0 [0..6] [410..5]

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Predicted Domain #1
Region A:
Residues: [1-142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSVRSIEDY FGQIESLLYR QDWTNGEKIS KFVSTYDEHA QEPFMHIEAY GSRSKRCRVS  60
   61 EDEVFDEIVC LHLHVLYNIH VAQDLITAQS TQIQIIQLFN KEILQKRKDE NWFLPIFYRL 120
  121 CTDLRWLSKG AEACVSGDDE GD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [143-335]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNANSFFESA AKAITECYRT CVSDVHAEEG TTKKVAMLNM TNQLFQIYFQ INKLNLLKPL  60
   61 IRAIDNCGSL YHDFLMSDKV AYNYFLGRKA MFDADLNLAE KSLLYAFRNC PADSMSNKRK 120
  121 ILIYLIPVKM FLGHMPTSQL LHEYRLDEFQ DVVAGVKDGN LAQLDGALAA NEAFFIKCGI 180
  181 FLMLEKLRMI TFR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [336-413]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLFKKVSQIV GTAQIPLDAF QTALRFVGVT DVDMDELECI IANLIASKKI KGYLSHQHQK  60
   61 LVISKMNAFP TLSGVSSN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.69897
Match: 1ufmA
Description: Solution structure of the PCI domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.69037212939381 bayes_pls_golite062009
transcription regulator activity 2.56741881949907 bayes_pls_golite062009
DNA binding 2.34112599257549 bayes_pls_golite062009
nucleic acid binding 2.25591323571311 bayes_pls_golite062009
transcription factor activity 1.72207203404871 bayes_pls_golite062009
sequence-specific DNA binding 1.1745827861852 bayes_pls_golite062009
transcription activator activity 1.07652525986046 bayes_pls_golite062009
protein binding 0.653872239015235 bayes_pls_golite062009
transcription repressor activity 0.181273085438029 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle